A short educational video by a board-certified dermatologist explaining differences between retinol, retinal, and tretinoin. It outlines the biochemical activation pathway (retinol → retinal → tretinoin), notes that tretinoin is prescription-only and the most aggressive retinoid, and mentions gentler over-the-counter alternatives for those who cannot tolerate stronger prescriptions.
Chapters
Your skin looks good, but it doesn't look great. I'm a board certified dermatologist and I want to help you level up your retinol game once and for all because I hear this every day. I just don't tolerate retinols. But do you even know which one you're using? Retinols are part of a class of vitamin A ingredients also known as retinoids and they're not all created equal. Let's understand this. Retinols are the inactive form. They need to get converted through two steps into the active form by first converting into retinal and then the retinal then gets converted into the tretinoin. Tretinoin is the active form of retinoids that is only available to you through prescription. This is also the most aggressive form. So if you're not able to tolerate this, we have over the counter options and I'm not sponsored by any of these brands. Retinols are going to be gentler than retinals because retinals like I just demonstrated have only one conversion step to become active.