Ashok Gupta's Retraining the Brain to improve Mental Health and Chronic Illness

19 Jun 2025 · 8 min
7:40

Interview with Ashok Gupta on Mind Health 360 describing his personal recovery from ME/chronic fatigue syndrome and the development of the Gupta Program (a brain-retraining/neuroplasticity approach). Gupta explains his hypothesis that the brain can become conditioned to maintain protective immune and nervous-system responses after an acute trigger (virus, toxin, injury), producing a self-sustaining loop of symptoms; retraining uses repetition/neuroplasticity to 'unlearn' those responses. He recounts finding Joseph LeDoux’s work, publishing a hypothesis online (1999) and in a medical journal (2002), and releasing the first commercial brain-retraining program (DVD) in 2007; he reports subsequent clinical studies and treating thousands of patients.

Questions this video answers

1999.

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2007.

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