Akkermansia and Metformin: Benefits

Name: Akkermansia and Metformin: Benefits
Uploaded: 2024-06-14T16:00:11+00:00
Duration: 32 s
Channel: Dr. Charles Mok
Description: This content was created by Dr. Charles Mok. This content was uploaded by Dr. Charles Mok. This is a YouTube clip titled "Akkermansia and Metformin…

14 Jun 2024 · 1 min

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This content was created by Dr. Charles Mok. This content was uploaded by Dr. Charles Mok. This is a YouTube clip titled "Akkermansia and Metformin: Benefits" (created 2024-06-14, last edited 2026-01-28) containing an English single-speaker segment. The speaker reports stool-test results showing good levels of Akkermansia, discusses its links to lower body weight and brain health, notes that low/intermittent doses can raise GLP-1 in the gut, and explains how this relates to metformin and semaglutide (possible synergy) as well as the reason clinicians often avoid starting metformin and semaglutide together due to gastrointestinal side effects.

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I did the stool test and I do have good Akkermansia in my body. People overweight tend to have low Akkermansia, but also Akkermansia is supportive for brain health, so I'm taking that too. Not for the same reason. In a lower dose and just intermittently, akkermansia can raise GLP1 level in the gut. Metformin raises GLP1 level by decreasing its degradation. Again, GLP1 is a target of the semaglutide, and it can be taken synergistically with semaglutide. We generally don't start semaglutide and metformin at the onset because both of them have the possibility of gastrointestinal side effects.