Dr. Charles Mok explains why people gain weight after hormone therapy and how to prevent it. Weight loss on GLP-1 drugs varies widely, up to 30% for some people. Those who lost the most weight kept it off, while those who lost little tended to regain it.
Chapters
Testosterone is a hormone that doctors might take for granted, just like we might not really assess the person's lifestyle when we're prescribing GLP1 agonist drugs. And if we look at the studies themselves, there was a big variation in the amount of weight lost by individuals over a period of time. And there were some people who lost very little weight, and people lost 30% of their body weight over a given period of time. And the people who lost the most weight very likely. Although the studies did not track this, had the biggest intentional efforts. In fact, when we see the long term studies where they took people off of their GLP1 agonists, the people that lost the most weight during the run in with the drugs were most likely to keep the weight off, and the people that lost the least amount of weight pretty much gained it all back.