
0:39
A short YouTube clinical commentary (Dr. Charles Mok) describing a biohacking-style protocol used at Allure: semaglutide is started at 0.25 mg for the first four weeks with stepwise escalation; weight loss often slows and tolerance arises around 12–13 weeks, at which point the speaker recommends stopping semaglutide (~13 weeks) and transitioning patients to metformin, often ~850 mg nightly. Metformin is noted for diabetes/prediabetes treatment and being studied for longevity.
Questions this video answers
0.25 milligrams for the first four weeks.
Around 12–13 weeks.
Stop the medicine at about 13 weeks.
Usually about 850 milligrams at night.










