A single-speaker medical explanation describing a stem cell therapy approach for arthritic joints: processed young stem cells are injected into arthritic joints where they counteract cellular senescence, reawaken inactive local joint stem cells, stimulate cartilage regrowth (visible on X-ray/MRI/CT), reduce pain, and improve function while bone structure remains unchanged.
Chapters
Now, there's been a lot of discussion on how this is working. The current stem cell technology takes young stem cells. They're processed in a certain fashion, and they're injected into the joint that has. That has arthritis. But even if you have bone on bone arthritis, there is some healthy cartilage in there that has inactive stem cells. And what's happening is that the sick cells that are causing arthritis are putting out a little juice, telling other cells not to grow, not to fix themselves, not to replace themselves. This is called senescence. And we cells in it actually wakens those live stem cells up in the joint. They start reproducing and start growing cartilage back. We see changes on X ray and MRI in CAT scan, where the tissues get thicker again, pain goes down, function gets better, the bones don't change, but the cartilage does get thicker.