Low Testosterone in Women

Name: Low Testosterone in Women
Uploaded: 2025-06-24T10:01:28+00:00
Duration: 45 s
Channel: Dr. Charles Mok
Description: A brief educational monologue by Dr. Charles Mok explaining that ovarian hormone production (including testosterone) declines and becomes erratic with…

24 Jun 2025 · 1 min

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A brief educational monologue by Dr. Charles Mok explaining that ovarian hormone production (including testosterone) declines and becomes erratic with age and repeated menses approaching menopause. The speaker states that ovaries produce most testosterone which is converted into estrogen, notes women aged ~20–50 have about 20 times more testosterone than estrogen, and discusses observational evidence from other countries where combined testosterone and estrogen therapy was associated with lower breast cancer in non-trial settings, motivating inclusion of testosterone in some HRT regimens.

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When a woman is in her youthful years, her ovaries are able to make all kinds of sex hormones. As you go through your eggs from having menses over and over again prior to menopause, your ovaries and the structures with the ovaries start to fail and the hormone production gets erratic. Low testosterone in women is also low estrogen in women. Your ovaries make most of your testosterone, then gets converted into estrogen. And again, women have about 20 times more testosterone than estrogen when they're 20 to 50 years old. And we always think about estrogen replacement, but came from testosterone. We saw in other countries where women on testosterone and estrogen, they had way less breast cancer than seen in these large trials in women. This led to the introduction of testosterone as a component of hormone replacement therapy in women.