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Dr. Charles Mok explains how semaglutide works for weight loss: you start at one-tenth the maintenance dose and ramp up over 20 weeks, when most weight loss happens. After that, weight plateaus between weeks 20 and 50 as your body tolerates the dose, raising questions about long-term use and cost.
Questions this video answers
Maintenance dose is roughly 10× the starting dose.
About 20 weeks to reach the maintenance dose.
Most weight loss occurs during the ramp-up period (approximately the first ~20 weeks).
Weight loss pretty much stops between 20 and 50 weeks.










