Short YouTube excerpt (multi-speaker) explaining that naltrexone blocks opioid receptors and will precipitate immediate withdrawal in people on chronic opioid medications (examples named: Vicodin, oxycodone); therefore it is not appropriate for current opioid users.
The only one you have to be careful of is if you're taking opiates, because it just blocks that receptor.
If somebody's on chronic opioid use, which would be like Vicodin or oxycodone, they should be using this because it'll block the effect of the opioids. Would it be pretty much 100% blockage? They'd get, like, withdrawals.
You go on instant withdrawal.
Fortunately, opioid withdrawal is not dangerous, but it's horribly painful. So somebody's got an addiction to narcotics or is on chronic narcotics. This is not for them. If you were not on narcotics and you took an naltrexone and you broke your leg, and you took a Vicodin an hour after you took naltrexone, it wouldn't really work. If you took it the next day, it would still work. It's the danger is just that somebody who's addicted to narcotics or who's on chronically, this is not for them.