Plasmapheresis Improves Alzheimer's

Name: Plasmapheresis Improves Alzheimer's
Uploaded: 2024-11-18T13:00:10+00:00
Duration: 46 s
Channel: Dr. Charles Mok
Description: A short YouTube segment by Dr. Charles Mok describing plasmapheresis (plasma apheresis) as studied in the AMBAR trials for mild-to-moderate Alzheimer’s…

18 Nov 2024 · 1 min

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0:46

A short YouTube segment by Dr. Charles Mok describing plasmapheresis (plasma apheresis) as studied in the AMBAR trials for mild-to-moderate Alzheimer’s disease. The speaker summarizes the procedure (removing/discarding plasma to reduce tau and beta‑amyloid, replacing with saline and albumin), reports that trial participants showed clinical improvement, and notes the trials were not powered for FDA approval—so plasmapheresis is not FDA‑approved specifically for Alzheimer’s though the procedure itself is FDA‑approved for other indications. The speaker names clinician David Hassi at the Maxwell Clinic in Nashville, TN as someone who performs the treatment.

Questions this video answers

David Hassi at the Maxwell Clinic in Nashville, Tennessee.

The AMBAR trials.

Saline and albumin.

Mild-to-moderate Alzheimer's disease (including mild cognitive impairment).

Chapters

One is called plasma apheresis. And my friend David Hassi is with the Maxwell Clinic in Nashville, Tennessee. He does plasmapheresis, which was studied in a big study called Ambar Trials. They took people with mild cognitive plan degree of Alzheimer's, like mild to moderate Alzheimer's, and they did plasmapheresis, where they extracted all their plasma out to pull these tau and beta amyloid proteins out, and they threw the plasma away and restored them with saline and albumin. They did this a few times over a couple months, and then they did it periodically. And they found that the people's Alzheimer's seemed to get better. Probably with the study was it wasn't powered to meet FDA approval. So it's not FDA approved yet. But you can go ahead and do it because the procedure itself is FDA approved. It's just not approved for Alzheimer's. This seems to improve Alzheimer's related disease and mild cognitive impairment.