Testosterone replacement therapy doesn't clearly increase prostate cancer risk, despite long-standing concerns. Men with the lowest testosterone often have more aggressive cancers, and some research suggests replacement may even lower risk, though evidence remains weak.
Chapters
When a man has prostate cancer, one of the treatments is a chemical castration where they give you drugs to markedly suppress the testosterone level. And this has led to some suspicion that, well, that's the case. Maybe testosterone replacement leads to more prostate cancer. This has been studied extensively. There's no link. So men with lowest testosterone have the most aggressive prostate cancers. That's a known. There's even studies treating prostate cancer with high dose testosterone. I'm not recommending that. But there are. These studies do exist. And it appears that testosterone placement does not increase the risk of getting prostate cancer. Does not increase the risk. It might decrease the risk, but there's not strong evidence to suggest that they're saying it does not increase your risk of prostate cancer.