Understanding Semaglutide Dosing

Name: Understanding Semaglutide Dosing
Uploaded: 2024-06-11T12:01:00+00:00
Duration: 34 s
Channel: Dr. Charles Mok
Description: Short educational YouTube monologue by Dr. Charles Mok explaining semaglutide (branded as Ozempic for diabetes and Wegovy for obesity), focusing on its…

11 Jun 2024 · 1 min

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0:34

Short educational YouTube monologue by Dr. Charles Mok explaining semaglutide (branded as Ozempic for diabetes and Wegovy for obesity), focusing on its dosing schedule and concepts of drug tolerance/intolerance. The speaker states that maintenance doses can be about ten times higher than early starting doses and that weight loss generally plateaus once maintenance dosing is reached.

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So I'm going to talk about semaglutide and pulsing the dose of semaglutide. So let's go over this drug. This is the drug also known as Ozempic for diabetes and WeGovy for the use of obesity or overweight with comorbidities. And the dosing schedule is very interesting. So we, we have something called drug tolerance and extinction intolerance. Drug tolerance is where you take something over and over again and you need more and more and then eventually stops working. This is classic with semaglutide. In fact, the maintenance dose is 10 times higher than than the early starting dose. Once you get to the maintenance dose, you generally don't lose any more weight.