What Are Senescent Cells?

Name: What Are Senescent Cells?
Uploaded: 2024-04-18T14:15:03+00:00
Duration: 42 s
Channel: Dr. Charles Mok
Description: Dr. Charles Mok explains how cells stop dividing after too many replications, then signal neighboring cells to do the same, driving aging and diseases…

18 Apr 2024 · 1 min

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Dr. Charles Mok explains how cells stop dividing after too many replications, then signal neighboring cells to do the same, driving aging and diseases like arthritis. Senescent chondrocytes in joints can be treated with stem cell injections or platelet-rich plasma to restore tissue function.

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Our body ages and we go through something called senescence in our cells. So your cells always replace themselves over and over again. As these cells turn over, errors are made in the genetic copying. And when that happens, the cell becomes senescent and it stops growing, it stops dividing, and it stops replicating. It also signals cells in an immediate area to stop replicating and stop, stop dividing. And this leads to organ dysfunction and then eventually organ failure. A classic example would be arthritis. If you look at these chondrocytes, the cartilage cells, they're senescent, they're just not really doing anything. We treat them by injecting stem cells or platelet rich plasma to try and do something to wake these up, so that's senescence.