This is a YouTube video titled "Estrogen and Cancer Connection | Mark Lintern x Dave Asprey" featuring a discussion between Mark Lintern and Dave Asprey recorded in May 2024. The content is a detailed conversation about the role of estrogen in cancer development, including its interaction with fungal pathogens, hormone imbalances, environmental estrogens, and their impact on health.
What is the role of estrogen in cancer? Can you talk about that a little bit?
So estrogen, as we say over in the uk, maybe it's a signaling molecule which, specifically for fungal pathogens, encourages their growth and virulence, which may explain why breast cancer is the biggest, most prominent cancer in women of all time. And then you've got prostate cancer as well, and with diabetes and what have you, you have this change in our hormones from testosterone in males to estrogen, because fat cells produce estrogen as well. So you've got this dysbiotic process going on with, with estrogen that facilitates fungal growth and virulence.
There's some really interesting stuff going on with estrogen. When I was heavily exposed to toxic mold as a child and in my 20s, when I was about 26, I had my estrogen levels tested and they were higher than my mom's and my testosterone was lower than hers. And then you realize that many of the most toxic forms of cancer make xenoestrogens that are up to 10,000 times more potent than human estrogen. So even men, we need some amount of estrogen. But if you're obese like I used to be, and for reference, I used to weigh a hundred pounds more than I do now, so that's 50% greater than my current 6% body fat. And I don't know what that is in stone, because you guys are weird over in the uk, but it was a lot of stones, we'll put it that way. So when I fixed my estrogen levels and increased my testosterone exogenously by injecting testosterone or using a cream under a doctor's care just to have physiological levels, not to be super physiological, I did see a lot of improvements in my health. So today we're soaked in environmental estrogens from plastic and chemicals, and even just from eating a lot of soy and foods like that. Do you think that excess estrogen in the environment is a contributor to cancer, or is it less important than what's going on with fungal estrogen?
I think so when you talk about synthetic estrogens as well, you're talking about them, them causing inflammation within your cells. So there's a whole process of this cell danger response going on where you've got this inflammation, you've got also the triggering of the virulence of particular fungal pathogens if they're present within that tissue. So, yeah, definitely estrogen hormone imbalance is playing a big role.
