NAD and nitric oxide are the molecules that drive sexual function. Nitric oxide synthase controls vaginal lubrication and erectile function by triggering the biochemical cascade that makes both work.
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We're the first to publish on vaginal lubrication. I did that in 2004, showing that this whole mechanism causes increased blood flow to the vagina and increased lubrication. And that's entirely dependent on NAD being there. So NAD drives sexual function and health? Yes, it was Vagradu. It prevents the breakdown of cyclic gmp. But what is making cyclic gmp? Nitric oxide. What makes nitric oxide? Nitric oxide is formed by the activity of the ECNO synthase, the nitric oxide synthase, which is present in the cavernosa of the penis. That enzyme requires NADPH in order to work the electron which comes onto nitrogen to make nitric oxide. That literally comes from nadph. So if you have NAD deficiency, you can take all the Viagra you want in the world. It will not help. Viagra is great if you're making nitric oxide because it prevents the cyclic GMP from being wiped out. If you don't have nitric oxide, forget it. And we know that Viagra doesn't work in everybody because some people cannot make nitric oxide.