Antibiotics: Too Much of a Good Thing?

In this brief presentation, Dr. David Perlmutter emphasizes the importance of using antibiotics judiciously. While acknowledging that antibiotics are life‑saving when applied correctly, he argues that Western, especially American, practices dramatically overuse them—both for minor ailments like sore throats and colds, and, more significantly, in animal agriculture, where about 70% of U.S. antibiotics are administered to livestock. This overuse creates two major problems: (1) the development of antibiotic‑resistant organisms that can cause infections without effective treatments, and (2) collateral damage to the beneficial gut microbiota that support reduced inflammation and optimal brain function, a theme central to his book Brain Maker. He concludes that antibiotics have a rightful place in medicine, but their use must be carefully considered to protect both microbial health and brain health.










