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In this brief video, board‑certified neurologist and nutrition fellow Dr. David Perlmutter addresses the common question of whether creatine supplementation leads to weight gain. He acknowledges that creatine can cause a transient increase in body weight, but clarifies that the gain is not fat—it consists of water retained within muscle fibers and the addition of lean muscle mass from enhanced protein synthesis. Perlmutter emphasizes that this type of weight gain is desirable for most people, especially athletes or those seeking improved strength. He also highlights his broader endorsement of creatine for brain health and overall metabolic function, while advising viewers to consult their healthcare provider before starting supplementation.

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