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In this brief presentation, Dr. David Perlmutter highlights the emerging evidence that gluten sensitivity can manifest as neurological problems even in the absence of gastrointestinal symptoms. He references the work of Dr. Marios Hadjivassiliou, published in Lancet Neurology, which emphasizes that many patients with neurological manifestations of gluten sensitivity lack classic gut complaints. Perlmutter enumerates a range of brain-related conditions linked to gluten sensitivity, including cognitive impairment and dementia, depression, headaches, movement disorders, ADHD, and chronic pain. He urges clinicians and listeners to keep an open mind and consider gluten sensitivity as a potential underlying factor for challenging neurological symptoms, quoting Louis Pasteur to underscore the importance of preparedness in diagnosis.

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