The Alzheimer’s Case Report We Shouldn’t Ignore

In this video, board‑certified neurologist Dr. David Perlmutter reviews a recent Frontiers in Neuroscience case report describing an 83‑year‑old Alzheimer’s patient who received a very large dose of psilocybin mushrooms. After an 18‑hour sleep, the patient temporarily regained the ability to converse, recalled aspects of memory, and regained bladder control—behaviors not seen for a long time. Dr. Perlmutter explains that animal studies show psilocybin can markedly increase neuroplasticity, the brain’s capacity to form new neuronal connections, which may underlie the observed improvements. He emphasizes that this single case is not a prescription for all Alzheimer’s patients but argues the findings warrant a more open‑minded exploration of psychedelic therapies for neurodegenerative disease.










