1:00

In this video, board‑certified neurologist Dr. David Perlmutter reviews a recent Frontiers in Neuroscience case report describing an 83‑year‑old Alzheimer’s patient who received a very large dose of psilocybin mushrooms. After an 18‑hour sleep, the patient temporarily regained the ability to converse, recalled aspects of memory, and regained bladder control—behaviors not seen for a long time. Dr. Perlmutter explains that animal studies show psilocybin can markedly increase neuroplasticity, the brain’s capacity to form new neuronal connections, which may underlie the observed improvements. He emphasizes that this single case is not a prescription for all Alzheimer’s patients but argues the findings warrant a more open‑minded exploration of psychedelic therapies for neurodegenerative disease.

Chapters

More from David

0:46
youtube.com

Your Brain Cannot Afford Bad Sleep | Dr. David Perlmutter

1d ago
0:51
youtube.com

Could Red Light Therapy Help Parkinson’s? | Dr. David Perlmutter

4d ago
0:35
youtube.com

Why Successful People Still Feel Invisible | Dr. David Perlmutter

1w ago
1:01:37
youtube.com

Why Successful People Still Feel Invisible with John Miles

1w ago
0:55
youtube.com

Is Dementia Really Inevitable With Age? | Dr. David Perlmutter

1w ago
1:10
youtube.com

Can’t Drink Coffee? You’re Not Missing Out | Dr. David Perlmutter

1w ago
1:03
youtube.com

The Brain Health Risk We Don’t Talk About Enough | Dr. David Perlmutter

1w ago
0:54
youtube.com

Is It Too Late to Protect Your Brain?| Dr. David Perlmutter

2w ago
1:03
youtube.com

Newsflash: Alzheimer’s Is Not Caused by What We Thought | Dr. David Perlmutter

2w ago
0:51
youtube.com

What’s Really Hiding in Your Food? | Dr. David Perlmutter

3w ago
55:43
youtube.com

The Diet Linked to Up to 50% Lower Dementia Risk | Dr. Austin Perlmutter

3w ago
See all content