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In this brief educational video, board‑certified neurologist Dr. David Perlmutter explains that muscles act as a “pharmacy” producing powerful brain‑health chemicals called myokines—specifically brain‑derived neurotrophic factor (BDNF), cathepsin D, irisin, lactate, and interleukin‑6. These myokines are released into the bloodstream and travel to the brain much like endocrine hormones, supporting neural function and lowering the risk of neurodegenerative diseases such as Alzheimer’s. The key way to increase the production of these beneficial compounds is through regular physical exercise, which not only builds larger muscles (thereby generating more myokines) but also directly boosts their release. Dr. Perlmutter frames this as a free, readily available brain‑boosting strategy and encourages viewers to subscribe for more health information.

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