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In this educational talk, Dr. David Perlmutter explains that migraine headaches are a major source of disability and lost productivity in Western societies. He critiques the prevailing medical model that relies primarily on abortive pain medicines and prophylactic drugs such as beta‑blockers, arguing that this approach often overlooks the pivotal role of lifestyle factors. Perlmutter highlights insufficient sleep and specific food sensitivities as major headache triggers. He details three categories of dietary triggers: nightshade vegetables (eggplant, white potatoes, tomatoes, and even tobacco), tyramine‑rich foods (aged cheeses), and gluten sensitivity, citing published research linking gluten to headaches. He urges clinicians and patients to assess and modify these lifestyle elements before defaulting to prescription medication.

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