David PerlmutterPresident,, Perlmutter Health Center · Board-Certified Neurologist | Functional Medicine Pioneer | #1 New York Times Best-Selling Author | International Speaker | Host of The Empowering Neurologist Podcast

What is the best exercise you can do for your brain?

24 Jul 2026 · 1 min

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In this brief video, board‑certified neurologist Dr. David Perlmutter explains that regular physical activity is one of the most effective preventive measures for brain health. He notes that while neurologists rarely discuss prevention, the evidence shows exercise supports cognitive function and protects against neurodegeneration. Perlmutter outlines a three‑part exercise regimen: (1) aerobic activity, which improves blood flow and oxygen delivery to the brain; (2) resistance training such as weightlifting or tension‑band work, which promotes neurotrophic factors and muscle‑brain signaling; and (3) flexibility work, which he stresses is essential to avoid injuries that could interrupt the exercise routine. By integrating all three components, individuals can maintain a consistent program that maximizes brain benefits.

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What is the best exercise you can do for your brain? Hi, I'm Dr. David Perlmutter. I'm a board-certified neurologist, and you know, it's funny, when I say that, I realize that this is not a discussion that neurologists typically have. Unfortunately, there's very little preventive neurology, but the reality is exercise, by and large, is great for your brain. And what are the specifics of that? Well, we know that resistance training, like doing weightlifting, using tension bands, etc., Also very good for your brain in addition to aerobic exercise. But I want to add in one third component here, and that is flexibility. Because if you don't engage flexibility, what's going to happen? You're going to get injured, and then the whole exercise program is, is done. So again, I believe it's a 3-way approach. That is flexibility, resistance training, and of course aerobics.