YouTube video (Dr. Lara/Dr. Lera Clone) describing stem cell therapy in dogs, illustrated by a clinical case (Mindy), an ~10–11-year-old female dog with tears in both ACLs (one surgically repaired). The speaker explains stem cell basics, cites a study reporting ~69–70% success when stem cells + PRP were injected for partially torn ACLs, and describes a new, minimally invasive blood-derived stem cell product used here (donor: a nine-month-old puppy). Treatment was given intra-articularly (knees) and intravenously; presenter notes observed functional improvement in Mindy and discusses potential broader uses (cartilage repair, reduced inflammation, organ/brain applications).
Questions this video answers
About 10–11 years old (speaker states "about a 10 or 11 year old female dog").
Approximately 69–70% success rate (speaker cites "69 to 70% success rate").
Nine-month-old puppy (speaker: "Mindy got the stem cells of a nine month old puppy").
Injected into the knees (intra-articular) and also administered intravenously (speaker: "we administer the stem cells in the knees... we also administered it in her veins").
Yes — both ACLs are torn; one has been surgically corrected and the other has not (speaker statement).
Chapters
Hey guys, My name is Dr. Lara. Today I'm here with Mindy. Mindy's a good girl, A good girl. Yes, she is. So Mindy is here because the topic that we're going to be talking about is stem cells. And Mindy is about a 10 or 11 year old female dog. And believe it or not, Mindy's. Both of Mindy's ACLs are torn. She's already had one surgically corrected, the other one has not been surgically corrected. And so just in case, if you don't know what stem cells are, what stem cells are, are they're cells that in theory could be programmed to become whatever. And so in this particular case, the. You know, with stem cells, when you have a torn ligament, one of the things I'm going to stand up because my knees are bothering me. Getting old, just turned 37 a week ago. I know, I know, I look great. Stop, stop. No, really, keep it coming. Anyways, so what ended up happening was when a dog shares an ACL usually, or damages the ACL usually, that once that that ligament is damaged, it is what it is. There was one study that was done where when they injected stem cells and PRP into a dog's knee who had a partially torn ACL, they, they had a 69 to 70% success rate in getting the ligament to completely heal. Now, if it's a complete tear, it's not going to go ahead and bridge the gap, but if it's a partial tear, there's a much higher likelihood that it may actually get to heal. Now the other things that can happen with stem cells is the stem cells will go ahead and help to repair the cartilage that's being damaged and worn down with the instability in the joint and all the inflammation that's already been going on. The stem cells also go ahead and help reduce the inflammation in the knee as well as helping to repair that cartilage. Now, when we typically administer stem cells, we go ahead and we administer the stem cells of that very dog to itself. In this particular case, we have recently joined forces with a company who offers stem cell therapy through the blood. And that is a very interesting proposition because now we're able to do stem cell therapy with a minimally invasive collection instead of before we had to do a mini surgery to collect fat. The other thing is, in this particular case, Mindy got the stem cells of a nine month old puppy. And so the thought is as you get older, you get less stem cells and your stem cells are not as good. And so we have noticed that she has. Mindy has had, like, a really remarkable recovery after we administered the stem cells. And we also, and mom and dad have noticed, like, she's doing things that she wasn't doing before. And so my thing is that this is. I think this is a really fun and exciting time to know that we have the ability to offer stem cell therapy and in a non invasive way, as well as being able to harvest it from a young dog and administer it to an older dog. They do do this, something like this in humans where they. They administer. They do blood transfusions from young people to older people, and they call them young blood transfusions. And it's actually a pretty interesting concept and idea. There's not a ton of science behind it that I'm aware of. I think they're just starting to go ahead and do that. And so this is something kind of similar to that where we're collecting the blood or the stem cells from a young dog and administering it to an older dog. Where do you administer them, Doc? So we administer the stem cells in the knees, and then we also. You can see that it's shaved by her knees. And then we also administered it in her veins. So it goes all throughout her entire body, not only just to her knees. So it will also help to repair some of the other things as well that could potentially be going on with her, like damaged livers, damaged kidneys. We're even considering starting to do this with some of our patients who have senility to see if it'll help repair some of the brain cells. So it's a really exciting time. Got any other questions for me, Abraham? Not for now. All right, guys, if you found this video helpful, please give us a thumbs up. Subscribe. If you know somebody who you think should see this, share it with them. Otherwise, be safe and thanks for watching.