Immunity + Metabolism

Jeffrey Bland explains how nutrition shapes immune function through cellular metabolism. Your immune cells have different fuel preferences: some run on glucose, others on fat. The gut holds two-thirds of your immune cells, making it the primary place to intervene.
Chapters
Immunity plus metabolism hey, have you ever had the cold and flu and felt like you were just no energy at all? Any ever wondered why? Why do you get so tired when you're not feeling well? It's because your immune system has been revved up. Because your immune system has its own metabolism that is activated to try to fight off whatever that infection is. And so this connection between your immune system and its metabolism is an extraordinary part of how your body actually works in your defense. And what is that metabolism? That metabolism within that immune cell or those immune cells? Because remember this is a very complex army of different kinds of specialists that protect you against illness and actually constantly search and destroy foreigners in your body. That that system is dependent then on how that immune system is being fed and how it's actually working will depend upon its status in the overall body. And that status is related to the nutrition and the factors that influence immune metabolism. We call that immunometabolism. And there is a field called immuno nutrition that relates then to how these all interface. So some immune cells prefer glucose as a fuel for their activity. Other immune cells prefer fat as the basis of their energy. And the differentiation of how those are fed can differ than how they do their job. So nutrition plays a very important role in modulating immune metabolism. So what does this all mean? What this all means is that we need to personalize and understand the immune identity of that individual and how we would then personalize their nutrition to promote appropriate metabolism to enhance their function of their immune system. So where does this all begin? Well, it begins with this complex place that where immune cells hang out. And where is that? It's 2/3 of our immune system hangs out in our gut. That so called gut associated immune system or gut associated lymphoid tissue as it's called. And that is the first place we might start thinking about where to intervene is to make sure that we're feeding those immune system cells that reside in our gut associated immune system properly and that then rel also to the microbiome that's interconnected to our gut immune system that's connected to our diet. Then from there we go on down this journey with the immune system into our liver and into our systemic circulation and into the various cells of the various organs, all of which then have their own immune system variations, all of which are dependent upon their metabolism for their function. This is exciting chapter that you're going to learn much more about through our big bold health immuno education program. So here's immunometabolism a part of how you're going to be learning from big bold health about how to manage your own and train your immune system to be that which you want it to be.










