66: Navigating Breast Cancer Screenings: Risks, Benefits, and Revolutionary New Technologies

15 Oct 2024 · 67 min
Episode

15 Oct 2024 · 67 min

0:00

Dr. Jen Simmons examines mammography's limits: major trials show little mortality benefit and substantial overdiagnosis. She discusses harms like radiation and false positives, recommends self-exams, and describes two alternatives: QT 3D ultrasound imaging and ARIA, a tear-based protein biomarker test.

Questions this episode answers

About 90,000 women aged 40–59; ~45,000 underwent mammography and ~45,000 did not.

In Nordic trials of ~600,000 women, for every 2,000 women screened over 10 years, approximately one life may be saved and about 10 women are overdiagnosed/overtreated.

Reported sensitivity ~91% and specificity ~57%.

Lesions with a doubling time of less than 100 days are considered meaningful/active.

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