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In this Mind Body Space podcast episode, host Dr. Juna Bobby (radiologist, educator) interviews her long‑time ENT specialist Dr. Jonathan Aviv about the sensation of a “lump in the throat.” Dr. Aviv explains that the symptom is often due to laryngopharyngeal reflux (LPR) and, more commonly, to acid influx—acidic foods and beverages that activate pepsin, an enzyme that can linger in the throat, sinuses, and mouth. He describes the biochemistry of pepsin activation below pH 4, the concept of “the pepsin story,” and how chronic exposure can cause inflammation, cough, hoarseness, and even increase cancer risk (Barrett’s esophagus, esophageal cancer). The conversation outlines a practical “dirty half‑dozen” list of acidic triggers (regular sodas, diet sodas, flavored sparkling waters, sports drinks, wine, and other flavored beverages) and contrasts them with three “healthy” acidic foods (citrus, vinegar, tomatoes) that can be neutralized with dairy‑based dressings. Dr. Aviv promotes the Acid Watcher diet, specific food‑based neutralization strategies, and two key therapeutic approaches: (1) an acute alginate product (Reflux Gourmet) that forms a raft in the stomach to prevent reflux at night, and (2) a chronic anti‑inflammatory blend of watermelon and cucumber to shrink throat swelling over weeks. He also discusses the impact of GLP‑1/GIP weight‑loss drugs (Ozempic, Mounjaro) on gastric emptying and reflux, offering both acute (alginate) and chronic (low‑acid, high‑fiber diet) mitigation. Throughout, he emphasizes the importance of proper diagnosis (laryngoscopy, sensory testing), patient‑doctor communication, and cautions against self‑diagnosis, while acknowledging the role of medications when needed. The episode blends personal anecdotes, scientific explanation, dietary guidance, and clinical advice to empower listeners to manage reflux without over‑reliance on medication or surgery.

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