
Calcium scoring misses soft plaque in younger patients and can be dangerously reassuring. A 55-year-old with zero calcium score had a severe widow-maker lesion visible only on cardiac CTA, which shows both calcified and soft plaque and measures stenosis.
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Let's talk about calcium scores, cardiac CT angiograms, my favorite thing to talk about. Gonna talk fast to get in 90 seconds. So calcium scores should be reserved— I don't care what any guideline says, I'm sorry— they should be reserved for people over the age of 50. Why? Because calcium takes time to form. If you are a 30-year-old and you get a calcium score and it is zero, we expect it to be zero. The calcium has not had time to form. You could have a cholesterol-rich soft, super yucky, super vulnerable plaque that has not had time to calcify yet. So if you get a calcium score and you're young, okay, it can make you think that everything's okay when indeed everything could not be okay because it hasn't had time to form. So a lipid-rich, soft, yucky plaque might not— well, will not show up on a calcium score. So my rule of thumb in my office is no calcium scores under the age of 50.. And I love, love, love cardiac CT angiograms. You take the same test, you slow it down a little bit, you add IV contrast. Now you see everything— cholesterol plaque, soft plaque, where the plaque is, what percent blockage it is, everything that you really can't see on a calcium score. So I'm going to show you this patient right here, 50-something years old when he had his test, and I believe he was 55. His calcium score would have been zero, and yet he has a yucky, nasty, nasty widowmaker, and he was completely asymptomatic. Cardiac CTAs for the win.










