Alzheimer's pathology starts decades before symptoms appear, silently progressing for 20 to 40 years. Gary Brecka shares how his mother's insulin resistance in her 30s and 40s set the stage for cognitive decline. Prevention in your 30s and 40s matters far more than waiting for late-stage drugs.
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When you begin to have these cognitive issues, that situation has been brewing for decades. I'm going through this right now with my own mother. I'm upset with myself in a lot of ways because she was insulin resistant and pre-diabetic for almost 20 years. I want to stop you right there, and I want your audience to remember what you just said. For 20 years, long before her cognitive impairment was noticeable. So that's what our target then needs to be. It's the people in their 30s and 40s who are watching us right now thinking, well, they've got time because Alzheimer's begins in your 70s. It does not. We are focused on the pound of cure. We're focused on the development of drugs to take care of people, to cure their illnesses, when just giving them the tools to prevent them 20, 30, 40 years prior to their onset really makes sense from an economic perspective. And it absolutely makes sense from knowing fully what you are experiencing right now, because I've been there.