Gary Brecka explains how low vitamin D3 weakens your skin barrier by disrupting filaggrin, a protein that keeps irritants out. When levels drop in winter, eczema flares increase because your skin becomes more permeable and your immune system can't produce the antimicrobial peptides it needs.
Several nutrients are absolutely essential for healthy skin and immune regulation, and when these are missing, your risk of eczema flares skyrockets. First up, vitamin D3. This nutrient plays a key role in producing antimicrobial peptides that protect the skin as well as regulating immune activity. Research actually shows that low vitamin D3 levels not only increase your risk for skin infections but also weaken your skin barrier, especially disrupting a critical skin protein called filaggrin. Without enough filaggrin, your skin becomes more permeable, allowing irritants allergens to get in. This is why eczema often worsens in the winter when vitamin D levels naturally decline.
Perimenopause Symptoms Can Start in Your Late 30s - Dr. Remina Panjwani | TUH 312
