Max Lugavere argues Alzheimer's stems from the brain's inability to generate ATP from glucose. Creatine replenishes ATP stores to address this metabolic problem, while anti-amyloid drugs offer only temporary fixes and carry risks like brain swelling and hemorrhage. He regrets creatine wasn't explored for his mother's condition.
One of the root causes of the condition, which we believe to be an inability of the brain to properly generate energy. So creatine, it helps the brain. It's involved in neuroenergetics, the brain's ability to generate ATP, which is its energetic currency. And in Alzheimer's disease, there's a stark inability for the brain to properly generate ATP from its primary fuel substrate, which is glucose. So with creatine, you're actually getting to the root cause as opposed to these anti-amyloid drugs. The risks are significant. Brain swelling, brain bleeds, and even death. Especially given your background and history with your mother. Had some options like this been available, maybe there would have been a different course. 1000%. I would have loved to have explored creatine as an option with my mom. And it's unfortunate the drugs that she were prescribed, I mean, were little more than biochemical Band-Aids. And I don't think that they helped her at all. In fact, I think they probably contributed to her net decline.
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