Gary Brecka explains that 70% of blood circulation happens through tiny capillaries, not the heart and major vessels. High homocysteine levels constrict these vessels, raise pressure, and trigger inflammation in the microcirculation, which can starve tissues of oxygen and nutrients.
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More than 70% of our circulation is actually not conducted by the heart. The 30% of our circulation that is done by the heart are our major arteries and our major veins, meaning there's pressure behind them to send blood to the tissues, there's pressure to return it from the tissues. But about 70% of our circulatory system is what we call microvascular. Even only a single cell can fit into this capillary system. What if this part of our circulation gets compromised? This is one of the reasons why we're so sensitive to high levels of homocysteine, a natural amino amino acid that can rise in the blood, potentially cause vasoconstriction, and drive pressure up. It's also why this part of our vascular system is hard to reach, and it's also why this part of our vascular system is so susceptible to inflammation.