Fasting, Fat Loss, and Fitness After 40 | Dr. Matt Chalmers’ Unfiltered Advice

15 May 2025 · 58 min
Episode

15 May 2025 · 58 min

0:00

Podcast episode (recorded May 15, 2025) in which James Laughlin interviews Dr. Matt Chalmers about optimizing wellness after 40. Core topics: the four "Pillars of Wellness" (biomechanical, biochemistry, psychological, spiritual); practical blood markers and tests to establish a biochemical baseline (notably insulin, testosterone/free testosterone, SHBG, hemoglobin/hematocrit); intermittent fasting approaches (time-restricted eating ranging from 16:8 to extreme 23:1/47:1), use of collagen and targeted supplements during fasting, and the hormonal logic behind fat loss (insulin vs glucagon). The episode also covers resistance and functional training for long-term mobility, measured approaches to anabolic use and liver/hematologic monitoring, and the therapeutic potential of cannabis and psychedelics for trauma and mental health.

Questions this episode answers

May 15, 2025.

Biomechanical; Biochemistry; Psychological; Spiritual.

23:1 (one meal/day), 47:1 (one meal every two days), and 16:8 (time-restricted eating).

Insulin: "below 10" (the lower the better, per Dr. Chalmers).

Bloodwork: CBC and CMP (plus hormones: total/free testosterone, SHBG, insulin, hemoglobin/hematocrit). Imaging: echocardiogram and calcium CT/CTA for vascular plaque assessment.

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