Joseph CascianiGeropsychologist, Consultant, Public Speaking, Freelance · Podcast Host of the Living to 100 Club | Clinical Strategies for Senior Residential Settings & Lifestyle Directors | Geropsychologist | Keynote Speaker

The Glycine Solution: Unlocking Health Secrets with Dr. Joel Brind

17 Feb 2025 · 1 min

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In this segment, the speaker explains how collaboration with the Oren Trek Foundation introduced them to the field of amino acids and aging, focusing on methionine restriction. The foundation’s research demonstrated that severely limiting the essential amino acid methionine in the diets of rats and mice leads to a substantial lifespan extension of 30–40%, albeit with reduced growth. These findings have been repeatedly replicated by multiple independent groups, establishing methionine restriction as a robust, reproducible phenomenon in rodent longevity studies.

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some work that I was doing with a, a foundation that was looking into something called methionine restriction. That's how I got into the amino acid and aging field. Hmm. This group called the Oren Trek Foundation, they had actually established a, a particular phenomenon that has been verified over and over again called methionine restriction, which is to say, if you feed or eat a diet that is, they found of course with experimental animals, rats and mice, if you have a diet that is very severely restricted, almost completely deficient in the essential amino acid methionine, the, the animals actually live 30 to 40% longer. Hmm. They don't grow to normal size, but they live 30 to 40% longer. And methionine restriction has been verified many times by other groups in both rats and mice. And it's, it's, so it's a thing as they say.