Joy Kong, MDRegenerative Medicine Physician, Educator, and Entrepreneur

A NEW Study That Gives Older Women Hope For Hormone Replacement Therapy!

23 Jun 2025 · 1 min

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Joy Kong, MD, discusses neuroscientist Lisa Moscone's 2024 study showing estrogen receptors increase in the brain after menopause, suggesting older women may still benefit from hormone replacement therapy. The research challenges the common 10-year window doctors use to prescribe HRT, proposing that women in their 70s could be tested for continued estrogen responsiveness.

Questions this video answers

June of 2024.

Estrogen receptors up-regulate in the brain (described as the brain being "hungry for estrogen").

The speaker cites "no more than 10 years post-menopause" and stopping treatment in women over about age 65.

Chapters

This is new research. June of 2024. There is a neuroscientist. Her name is Lisa Moscone. What she's found in this groundbreaking study she did was that estrogen receptors up regulate in the brain. What that means is that the brain is actually hungry for estrogen. This woman has basically created a marker that didn't even exist. What this means is we could potentially extend that window of opportunity which is often heard or said in the hormone replacement therapy space where Nothing more than 10 years post menopause or stop treatment in women over the age of 65. That's that window of opportunity. And so what we're seeing now is, well, wait a second. What if we test the brains of women who are 70 or 75 to see if they're still hungry for it? To see if they're still hungry for it? Because that can then change. Okay, this window of opportunity I see. Because why do we have to stop giving hormone replacement therapy to women.