Dr. Joy Kong explains how MUSE cells act like guided missiles to find injury. When organs are damaged by stroke or heart attack, they release a chemical signal called sphingosine-1-phosphate. MUSE cells sense this signal and travel directly to the wound, leaving healthy tissue untouched.
When an organ undergoes acute injury or chronic degeneration, like a stroke or myocardial infarction or severe liver damage, et cetera, the damaged cells release a specific stress signal called S1P, and the mu cells possess surface receptors called S1P receptor 2. And these cells can be injected into the bloodstream and they act like a guided missile detecting the S1P gradient and travel directly to the site of injury and completely bypassing the healthy tissue.
