Mona SharmaCelebrity nutritionist and wellness advocate

The Fat You Actually Need? Why C15:0 Might Be the Missing Link

12 May 2025 · 0 min

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Stephanie Venn-Watson and Mona Sharma discuss C15:0, a fat linked to cellular fragility syndrome, a nutritional deficiency that may underlie metabolic syndrome and fatty liver disease in both humans and dolphins.

Questions this video answers

It is the first nutritional deficiency syndrome to be discovered in 75 years.

As many as one in three people (≈33%).

One in three people with fatty liver disease are thin.

A couple of months ago, we published what's called cellular fragility syndrome, the first nutritional deficiency syndrome to be discovered in 75 years. We're seeing the same combination of changes happening in people. I think as many as one in three of us have C15 deficiencies, which are resulting in the cellular fragility syndrome, which then leads to this whole combination of metabolic syndrome and fatty liver disease. It popped up in the dolphins at the same time. Wow. Yeah.
And these are diseases too, where in seemingly healthy people from the outside, they're now showing up metabolic dysfunction, fatty liver. For people who are non alcohol drinkers.
One in three people who have fatty liver disease are thin. In fact, it's the people who are thin that have this disease are more likely to have the most aggressive forms of this disease.