Josh TrentIdentity Transformation Architect and award winning Host of the Wellness + Wisdom Podcast—a decade-strong show with over 750 episodes and 15M downloads.

Metabolic Myth #1... #caffeinefree #metabolicsyndrome #metabolism #metabolichealth #longevity

7 Mar 2024 · 1 min

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This YouTube clip (uploaded by Josh Trent, Mar 7, 2024) argues that most disease is driven by metabolic—not genetic—factors. The speaker claims “99% of disease is not genetic,” attributes poor health and accelerated biological aging to metabolic dysfunction (stating 87% of Americans are metabolically dysfunctional), and links mitochondrial damage (a “trifecta” of oxidation, glycation, and inflammation) to heavy caffeine use, sleep debt, adrenal fatigue, and downstream effects like decision fatigue—framing a downward spiral of worsening metabolic and mitochondrial health.

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99% of disease is not genetic in nature. It's metabolic in nature. The more mitochondrial dysfunction there is, the more metabolic dysfunction there is. 87% of Americans are metabolically dysfunctional. This means faster biological aging over chronological aging. So your propensity to get any and all diseases is much higher when you're metabolically dysfunctional. You're going to see when you're in these states that you're going to have what I consider like a trifecta of damage on the mitochondria, which would be oxidation, glycation and inflammation. And those all are connected to disease and aging. That's going to happen over time with just this heavy caffeine consumption. And then think about when you're in these states of sleep debt and caffeine consumption and adrenal fatigue, you're going to have decision fatigue, these kinds of things that are going to have an impact on you in terms of your long term well being. And so this is the downward spiral. 99% of disease is not genetic.