Decrease Inflammation by Lowering Galectin 3, with Dr. Isaac Eliaz @dreliaz

Foreign.

Welcome to this episode of the five Journeys podcast. I'm Wendy Trubo, this is my co host at Levitan and today we're really psyched to have Dr. Isaac Elias back. We, we love him personally and are having him on the podcast today. He is a leading expert in the field of integrative medicine specializing in cancer detox immunity complex conditions. He's a respected physician, researcher, best selling author, educator, mind body practitioner. He partners with leading research institutes including Harvard, National Institutes of Health, Columbia and others. And he co authors studies on integrative therapies for cancer, heavy metal toxicity and others. And he has a new book out the Survival Paradox. We're going to talk about that today and also products that help with detox. So Isaac, welcome. What a privilege to have you back.

Thank you so much for having me. I loved our conversation and our connection and I'm looking to, to see it flourishing.

Yes.

So I want to be, I want to clarify you're saying having them back but yeah, we actually had, we interviewed you for our summit.

Right.

That we or upcoming summit in April. So people that we're going to be publishing this way before April.

Yeah.

And really look forward to. We had an amazing conversation that I know Wendy and I learned a lot about and looking forward to this conversation.

Yeah, we love chatting with you. So welcome back.

Thank you.

Anything we majorly missed in terms of your bio?

No, it's, it's great. I think, you know I'm, I'm. I started my journey in integrative medicine in healing arts at the age of 15. So a little bit early. So I think what, what I'm sharing now in my early 60s is a reflection of this multiple decades of being a physician, a licensed acupuncturist, trained vertically in multiple medical system, many decades in mind body medicine and being an active researcher with some large NIH grants right now researching specifically the effects of removal of the Survival products Protein Galectin 3 through therapeutic apheresis and what it does for sepsis. So with this in mind over the years, especially in the last few years, I've come to the recognition of how critical detoxification is. And so a big part of my book, my first solution chapter in my book after I introduce the issue of survival paradox, the paradigm and how it works and different systems and diseases that affected by it. The first chapter in the solution is detoxification. So I think it's important for people to recognize that it's not just a technique, a method. There's a reason why it's the first step, because it is the first step in our physiology. It's the first step in order to create a change. We need to create space. One of the biggest mistake of detoxification is people have the same lifestyle and they are very busy and they're trying to put detox into a busy life. It's not going to work. We need to create space. And the only way to create space is by letting go. It's by cleaning what's crowded. And that's the value of detoxification. So when we come to this world, the first thing we do is we take exhalation. We let go. It's the most basic detoxification process. We do two thirds of the time. Right. Exhalation is twice as long. Inhalation. The last thing we do when we leave this world is we take an exhalation. So this process of letting go that allows for something else to happen is so fundamental. And what I'm finding when I kind of contemplate it, preparing for this podcast and thinking about the process as I meditate, it's profound. The power of detoxification is so profound because the depth of the letting go that can happen is so deep on so many levels. And then we have a choice. Do we do it with the mind? Do we do it with supplement? Do we do it with food? How integrated by the understanding that when we let go, so many possibilities open to us. Right, Right. I mean, you know it, we've talked about it, it's amazing. So that's why it's important for people to see it beyond or do this colonic or do this nmr or take this supplement. Understanding, it's really in order to transform, in order to nourish, we need to detoxify.

I think.

Yeah, you're talking language.

Well, I mean, I, I love the idea that because we mostly talk about detox from a biochemical point of view. And what you're talking about is really not only lifestyle, but when I think of creating space, I think of meditation practice, I think of acupuncture, pressure practice, but I also think of just plain yoga.

Right.

And one of my first introductions when I first got into yoga was, okay, you're gonna stretch, and then you're gonna stretch some more, and then you find space and you are able to stretch into that space because you, you allowed yourself with the breath, you allowed yourself space. So that's. I agree, for me, like you just added another. It's pretty profound that it's not just biochemical, but it's really the whole, the whole process.

And I heard something thoroughly different.

Haha.

Because I heard, I heard that you can't put detox into a life that's too full.

Yeah. So it's interesting, you know. Yeah. You got me into yoga. I started practicing yoga at age 15 and I was a yoga teacher for many years. I trained yoga teachers for many years. I'll send you guys some pictures. I still teach yoga now in my retreats, even if I'm not very flexible. So you said something profound that not many yoga teachers often recognize. You know, there are two basic systems that are used very often to create space. Qigong and yoga. And in qigong you really are trying to find quietude in the movement in your. In yoga, you are trying to find movement in the holding of the asana. So when you get to the place, when you are stretching, you try to find the space right there when it's open. That's so true. And what I'm finding is the more we know about a topic, the more we understand the biochemistry, the more we understand physiology, the more simple. Exercise has a great profundity because you mentioned the space in yoga, but there is a space within our body. There is good space in the circulatory system. We don't have atherosclerosis. The blood is circulating very evenly. If we have good space in the extracellular space, the space outside the cells, there is no clumping, there's no friction, there will not be inflammation, there won't be a sense of, oh my God, we're not getting good supply. We're in the survival mode. Macrophage will be relaxed, insulin receptors will work well, AMPK will be activated. The mitochondria gets a sense of everything is clean and spacious. I have time to produce energy in an efficient 3600 ATP per every glucose without producing toxic byproduct. Right. But if the cell is at a sense of, my God, there's no space, what happens? There's no air where there's no space. When we are hypoxia, inducing factor comes in, right? And then PDK gets stimulated and then the mitochondria is blocked. And then suddenly we get unhealthy metabolism. And based on our genetic epigenetic, which highway we are on, it will lead to different diseases for different people. So the process of detoxification is a mental process in the deepest way. And the deepest way is when a thought ends. Can we really let go and not stick it to the next thought, not make it sticking, which is a tendency of holding is a basic driver of survival, of course, because what is survival? Survival is not letting go of something that has a beginning and has an end. That's really what it is. It's. And by the same thing, then we'll go into the biochemistry and the extracellular. And that's the importance of the survival paradox as a paradigm and the blocking of galectin 3 with modifiedin as a biochemical solution. Biochemical response to a very profound concept. But my goal when I speak is I don't want to limit this to just a chemical, physical disease because it's all interrelated and we are. We are very much in sync, you know, from our philosophy, from our belief in this multidimensional. So, yeah, creating space is what allows things to happen. Definitely.

Go ahead.

You've mentioned Galectin 3 a few times, so I was hoping you could talk more about it. You talk a lot about it in your book the Survival Paradox. So can you, for our listeners, talk about this and why it matters, what, what difference it makes? How do we impact?

What is it?

Yeah, of course. So Galactin 3 is a carbohydrate binding protein. It's the most researched lectin. You know, people know about lectins and people can. People can be allergic to lectins, but it's something that came into the attention, you know, lately. But I've been involved with collecting research for almost 30 years and what galectin does. So there are different galectins. The most researched one is Galectin 3, which is about 10,000 published paper. So galectin, I coined it our survival paradox protein. And why? Because when we go into a survival mode, we are all built to survive. That's how we survive every cell in our body. And we respond to survival automatically through the central nervous system, through the autonomic nervous system, either with fighting, which equates to inflammation, to struggle. That creates kinetic heat. It creates a lot of density. There's no space. When you fight, there is contact, or we run away. We hide and create a shield, a micro environment, a biofilm, a lattice formation that is actually biochemically and structurally created by galectin 3. Galectin 3 is the protein. It has a place where it attaches to different carbohydrates. It creates pentamers, five of them. It attaches to each other and you literally create a coating which allows bacteria to hide, viruses to hide, parasites to hide, heavy metals to hide mycotoxins to hide emotions to hide and create toxic environments. If we detoxify and we don't dissolve these areas, it won't work. So what the Galactin 3 does is once the nervous system, if we go into a sympathetic mode, we can take a deep breath, do yoga, and we go into pure parasympathetic mode. But biochemically, once it turns on, it doesn't turn off so quickly. It turns on within minutes by Galectin3 going up and recruiting the immune system. I've shown in research I've published that galectin 3 spikes before interleukin 6. When we block galectin 3, we prevent the spike of interleukin 6. In fact, that's the whole approach to treating sepsis. So we got this alarm protein that helps us with survival by how, by creating inflammation as an immune response. Immune dysregulation example is what's happening with COVID right? So many people are struggling with it. And by creating a shielding a micro environment that leads to fibrosis, to dysfunction, the Galectin 3 is like the alarm that goes to the place where there is problem. Different nasty ligands, inflammatory ligands, immune modulating ligands, sticky ligands that creates stickiness between molecules called integrins. They all are brought by galactin3 and you create a different microenvironment for people to understand. It's like a different physiology in a certain part of the body, right? People say, I was so healthy, I woke up one day and I had cancer. Well, it didn't happen one day. Certain reasons led certain areas to develop a certain micro environment where the body couldn't control it anymore in a healthy way, in a spacious way, Wendy, like we mentioned. So it reverts to survival. It tries to to deal with it through inflammation, which creates mutations which can create cancer. So that's why when you block Galectin 3 because it's an upstream, it's at the beginning, it's like shutting the waterfall of the immune dysregulation compared to trying to address different cytokine, which is like catching a waterfall with a bucket. Not an efficient idea. So that's the importance of Galactin 3 and addressing it. And in end, when we are stressed or in a survival mode, stress, emotionally, physically, injury, toxins, anything that causes us to function in a disharmonious way, it will affect Galectin 3. And the thing with Galectin 3, because it's an upstream molecule, you need very little change to create a mega change in the downstream cytokine, the downstream molecule that does the final damage. And again It's a testament to the upstream role of galectin 3. Galactin 3 will go up by 20%. 30% sometimes will double. Interleurkin 6 will go up a thousand fold because it's a downstream cytokine. So that's the importance of Galectin 3. And if I wasn't clear enough, please let me know.

So are we looking at preventing Galectin 3 from being released or are we looking at quieting it once it's released or both?

We're looking at quieting will be. But once the system gets quiet naturally, less galactin will be released. So when you use modifiedin you won't necessarily see a reduction in Galactin 3. What will happen is that the modifiers. It was pectin because it has galacturonic acid itself. Pectin is a long chain of galacturonic acid. It's a sugar, six carbon. It's not glucose. It's a long chain and it has side chains, different side chains, but it doesn't get absorbed. It's too big. We chop it to a very specific size and a very specific structures. That's why pectasol is a. All the research was done on pectosol, about 80 published papers. So then the galacturonic acid in pectosol will come to the Galectin 3, will dislodge the nasty ligand and will break the pentamer. So now Galactin 3 is blocked. It cannot cause damage. When it doesn't cause damage, once the inflammation goes down, then Galactin 3 will go down because the body's alert system is finally quieting down. So I remember I came from a, from one of my trips to Tibet where I was too high and had really lack of oxygen and had, you know, severe palpitation, probably from lack of oxygen. And I was in a survival mode. I mean, I had, I mean it's an interesting. You know, sometime when you give, you get back, sometimes you don't get it back. Sometimes you get back very quickly. So usually in these regions there's no electricity. But as I went up that time, it was 2015, I found out that the remote areas I'm going to have electricity. So I told my daughter, wow, we really need to buy an oxygen generator for these people. We are treating some very sick people. Getting oxygen is going to save their life. So we bought an oxygen generator and they gave us a gift, a pillow that you fill with oxygen and you breathe. So we filled the pillow. Sure enough, it saved somebody's life a few days later. I just didn't know it's going to be my life, you know. So I remember the sense of driving down, having one pillow of oxygen I have to manage until I get 1,000ft from 15,000ft. It was quite the journey. And Galactin 3 went up from usually minus 10, 11, it was 17. So once I went, you know, into my regimen and I did therapeutic apheresis, I needed something more dramatic to really clear the body. Then, yeah, my symptoms went away. My Galectin 3 relaxed back to 11.

How often are you checking your own Galectin 3?

I check it every few months. It can change in 20% of the population every three months. But it's really important, critical and essential. I made my point for people to realize you don't decide if to use or not to use modified citrus pectin. Pectosol. Based on level of Galactin 3, who needs to use pectosol? Anybody who is breathing, literally. Because as we age, as we go through trauma, as the body is repairing, it mobilizes Galactin 3 and causes damage. Centurions have lower level of Galactin 3 than people in their 70s and 80s. It would help us to really get. It has a direct factor on longevity. It's not the topic. I don't want to go into it too much. So we need it anyway. The levels are very individual and they are based on expressions of methyloproteinases and the ratio between pentamers and monomers. So you can have a low galectin 3. It doesn't matter. You need to block it based on your health. So if you're very healthy and you know, let's say in your 40s at the latest 30s. 40s, very healthy, no issues. Yeah, five grams a day would be enough. If you have any of the chronic inflammatory degenerating diseases, high toxicity, then you got to take the full dose of 15 grams. The reason for checking the Galectin 3 is that for certain people, Galectin 3 is not only a prognostic indicator of what will happen in the future, but it can help us to follow the disease. For example, metastatic cancer sometimes, or autoimmune diseases. In These patients, following Galectin 3 will tell us how much better they are doing. And the other category, you may have a healthy patient, you do a Galectin 3, it comes back elevated. And this means there is a time bomb going on. And once you. So you need to assume they have inflammation and fibrosis somewhere Once you treat them, you will see Galectin 3 will come down, will come down. And so this is really why you do it. If you have somebody who is healthy, but Galactin 3 is elevated and what is elevated? Do not rely on the standards in the labs because the standard in the labs were based on the approval for heart failure. Patients with heart failure that were tested in very high percentage of kidney disease, very high percentage, certain level of chronic kidney disease. The galectin 3 doesn't get excreted as well. The standard of under 17.8 being normal, no way. Anything about 12 you get concerned, especially now when it's automated. Every lab does it, it's automated, the values went down. And I know as somebody you have seen thousands and thousands of dilating three results. So that's a little bit about the relationship between Galactin 3 and use of modified citrospect.

So I'm assuming people with like chronic fatigue, fibromyalgia, Lyme disease, all those people are sky high. Galactin 3, very interesting.

So Lyme disease is not the case. Now Lyme disease are the category of patients that maybe benefit most or close to most from a modified tetraspectin. We have large Lyme clinics where now every single patient gets pectasol. Why? Because you don't get the Herxheimer reaction. And why? I mean universally. And they can tell you wow, my mental, I'm clearer mentally because galectin 3 disrupt blood brain barrier, activates microglia, causes neuroinflammation and activates inflammatory post perfusion lack of oxygen to the brain. And because of the effect of MCP on the biofilm. But the reason is when you give a regular binder, it's like you take all the drawers in the kitchen and you throw everything on the ground. It's a mess because you peel off. And that's why people get a reaction. You know, it takes time to clean up modified, regulates, attenuates, lowers the dysfunction of the immune system, the over inflammatory response. You get something that is calming, that is balancing while it's cleaning. And it has a great affinity for heavy metals. I've published a lot of this with the usda. So you can use it, you can add other binders, but it's, it's so much beyond the binder because of its other effects on galactin 3 and on immune regulation, which is key. It's not, it's not only immune enhancement. Immunisment is a double edged sword because you know, when you turn the fire, it's going to burn everything. It's about immune regulation in survival. We got to survive. The body does the best to survive. That's very important for people to realize. Especially when you look at things from the past, the traumas, and say, why did I do it? Why did it happen? Well, this was the best you could have done at the time. That's a principle of survival. Now as part of detox, we are in a different place, we're in different time. We can allow ourselves to let go. It's not easy. Why? Because there are neurological printed patterns in us multigenerational, you know, as the Holocaust. The, you know, my, my grandfather, my, my grandparents being in the Holocaust, my mother escaping. And I write in my book Healing the scars of survival how I healed from my grandfather's trauma. So part of this multi generational healing is part of detoxification. And again, we have only an hour. But I can go so much just on this topic because it's a lot of what I teach in my retreats is how to, how to create a multi generational healing.

Every time we talk I have to take citrus pectin, you know, and then I. So when you're looking at detoxing people, are you. Is. Is citrus pectin the foundation of what you're using? Modified citrus pectin.

So if you look at my programs 15, 20 years ago, I used a lot of supplement. I didn't always use pecto sal modified. Now it's automatically my first supplement for anyone because you cannot get it through food. And it addresses, if you saw the list of diseases that it's affected and it addresses it at the top. And because of this, if you look at research, let's say in oncology, you see there is. And some of it, we publish some of it. Other centers, you can see it works synergistically with multiple chemotherapies. It works synergistically with radiation therapy. How does it happen? Because it allows the body to heal itself. For example, we just presented the biggest cancer conference in Europe, our multicenter trial from six different oncology centers in Israel on biochemical relapse of prostate cancer. 18 months. That's a long time compared to baseline. How much we were able to slow down the progression or stop it and reverse it. 90% of the patient had benefit. 9 0. Now MCP didn't kill any of the cancer. It's not what it does. It allowed the body. Because what is biochemical relapse for people who don't know, you take out the Prostate with the cancer, there's no cancer. PSA is zero. And then it starts coming back. You know, it's cancer, there's no prostate, and then it's just beginning. Usually a little bit more aggressive than the original one. And now you're giving the body something that allows it to address the issue by itself by fine tuning the immune response, reducing the inflammation. And the body does a very good job. And so that's an example in one area. And so this is why it's so important. It's something I take every, every single day. Sometimes I get lazy. I don't take 15 grams. I take just my morning dose, but then I take seven and a half grams, which I already took this morning.

So it doesn't have to be with food or without food or it doesn't really matter.

It's better without food, but it doesn't, it's not critical. Even 10, 15 minutes before food is fine. So I take it as part of my pre food routine in the morning and before bedtime. It's very good before bedtime because you get a lot of also help with the gut and the gut connection.

Can you take too much?

No. Now, people are smart. And just like I said many years ago in a big medical conference, the job of the doctors is not to stand in the way of the patient. Regular doctors do so much part of detox might we hold to concepts. So as part of it, certain patients had a high level of Galectin 3, they were not responding. Certain prostate cancer patients were not responding to modified cytospectin. And one, two of these very smart people said, you know, I have a lot of Galectin 3, I'm going to take 25 grams. Sure enough, they started responding. So people with very high level of Galectin 3 above 20, unless it's from kidney failure, we'll need to take more. You just have more. There is more to clean. You need more cleaning agent. But once you are better, you can definitely go down to a lower dose, but you will feel a difference. For example, Galectin 3 was going to be approved by the FDA as a marker for a risk factor for diabetes, just as the company who developed the essay went out of business. So Galecan 3 affects sugar metabolism. If you take enough modifiedin, you will see in your patient a reduction in hemoglobin A1c. It may not be dramatic, but it's done with an extracellular effect that has an intracellular effect, and that's the beauty. So you can combine it with your intracellular Detox stuff or nokiol, curcumin, berberine, you know, quercetin, the things that affect, you know, the different pathways. So I, so when I, when I treat people, I mean, I see all this pathway into a cellularly, but I also see, you know, their pathways outside and it's all together.

So do you find.

I know this is fascinating. So I know that our patients listen to our podcast. So I know we're going to get some requests for Galectin 3. So I guess my biggest question would be, as we're checking this on our patients, because we're going to start, do we. Are there any times where we want to say to people, we don't want to do this until you're out of this situation? Or if you just had a big bender or is it fasting? Not like, when are those times not to do it because it's going to.

Be falsely elevated anytime they got a scar.

Scar like a surgery?

Yes, yes. So if somebody, you can have, people who are healthy had a scar 30 years ago, they don't tell you and they have high galectin 3 and you ask them and you look and you'll find, oh my God, my scar has been itching for 20 years. Right. We see it's still red. And when you do neural therapy into the scar and you calm down the scar, the Galectin 3 will come down. Absolutely. So scarring. That's why my second chapter addressing the scars of survival. So we have the physical scars and that's why neural therapy is so profound, but we have emotional scars and psychological scars. And that's why we started with detox. And we know we're going to end with detox because detox is about letting go of scar, because scar is a stuckness in a place that they're not supposed to be hardening. Right. There's no flow with the skull. And you know, for me, it's kind of mind blowing how when you inject somebody's skulls that they had 30 years ago and it gets thinner and it never comes back? So some people talk about membrane potential, you know, and proc and doing it. But for me, I go to the very different realm. The local tissue is stopping, giving feedback to the brain that there is a problem because you numbed it and the brain lets go and it doesn't reassemble the same memory. So it's really. Every single patient will have some level of improvement in the scalp from 10% to 80%. But whatever the improvement is, will never come back. That's the Process that we are all together trying to initiate and support in the process of detoxification is letting go of what is not needed, right? That's what detoxification is, getting rid of toxins. And within it, we have to recognize that as we detoxify, as part of our metabolism, we are producing toxins, right? And we are bombarded with toxins, heavy metals, industrial pollutants. For this we can have some control. We can have HEPA filters, we can live in a clean place. We cannot run away from pesticides, by the way, even if we eat organic, they are everywhere. All of us have glyphosate. And that's the importance of glypho detox and the effects on the gut. I won't go into this and using it together with spectosol. So if we realize this one, ask ourselves, is there a way where we can really get rid of toxins so they don't come back? And there is no, because you keep.

Getting exposed to more. So how.

No, no, I'm going somewhere, you know me, I won't bring something.

I feel like I have to give you like a drum roll.

So it's not that we get rid of toxins, but if something which is toxic becomes non toxic, then there's no longer toxicity. So one of the biggest steps psychologically, and it's a big step in meditation, is acceptance. The more we accept things that usually trigger us to reactivity, the less things are toxic to us. There are certain things that upsets us and then our blood pressure goes up and our norepinephrine goes up and our glucose, that's a toxic reaction. We all agree if we just accept it genuinely and it just doesn't trigger us, we just had less toxins, right? So the organs that does it in the body is the heart. Because the heart takes all the dirty blood that everyone doesn't want with an open heart, right? Otherwise we'll be dead. Right now on this podcast, takes from everywhere. And it needs to take, otherwise it can't function. It needs the pressure of everything that we don't want coming from our past. Because it's coming, right? Whatever comes to the heart has happened in the past in the cell either five minutes or 50 years ago. If it's a certain food or experience that created a certain molecule that affected the cell, that now that's why when you do detox, right? You know so well, people have memories about the path and things come out. The cell is letting go. We connect with the universe through the breath. The power of connecting with the universe, which is credible. And then the heart takes the clean blood and it gives it everywhere. And once it gives it and it relaxes, it nourishes itself, closes to the heart through the coronary artery. So the heart nourishes itself in order to nourish others, but selflessly after it's done. So when we connect with our heart, we start to transform the toxicity. So in meditation, it's a practice of tongling, of taking suffering and create and giving love and compassion and healing. So the reason why people learn it so quickly, because we are built to do it. You know, it's the tikkun, the fixing in Kabbalah, in Judaism. So connecting with our heart is very, very important. For me personally, I had pain here all my life, since very early age, until a few years ago. And I knew it's not mine until I realized this from the trauma of my grandfather from the Holocaust that just. He died from stomach cancer when he was 52, 53, because he couldn't stomach the trauma. My grandmother survived another 50 years almost. And on a graveside, my mother suddenly told us, you know, your Grandfather Hitler killed 10 out of the 12 siblings. We were never told, can you imagine? And he just couldn't stomach it. It was never talked. And when I did my work with it, being aware of it, my chest suddenly opened up. You know, like after 50 years, you know, it's not common. And I could feel this opening. But what was interesting, and it was related to letting go of the trauma of the Holocaust, accepting it, having a certain level of forgiveness, which is hard for, to even express, because people say, how can you, how can you go through such a thing? And once it happened, my mother, who could never watch any programs on the Holocaust, was able to suddenly turn on the TV and watch programs on the Holocaust. I didn't tell her what I went through, but because it was a multi generational healing, it went backward to generation and came back one generation, which we know scientifically happens. That's the power of detoxification. So when we get the heart into the process and we create space and we define what we want to detoxify, and we become more forgiving to ourselves and to others, we become self loving as part of loving others, not as part of a narcissistic approach, then anything and everything is possible. But it starts with detoxification, right? It started with the letting go on the cells and when they're out taking it in. So that's why detox is so basic.

I have a question. How can we bottle this.

I love talking to Isaac because like.

How do you go from biochemistry to multi generational healing to self love, to compassion, back to biochemistry.

This is really like, this is.

I want to bottle you.

Yeah, this is, this is what I teach, you know, so I, I do it in a retreat environment a lot in Israel for a decade. And now in 2023, probably in the second half, I started doing in the United States. There is a way, in the right environment, few days of the right diet and the right environment and the right explanation and meditating and exercise. It's amazing what happens, especially in the level of multi generational trauma. I mean, things that are too wild to talk in public. But when, when we get together, I'll tell you things that you think are impossible. Now, as somebody who was fortunate to treat and study from the greatest meditation masters in the Himalaya, you know, that are not alive anymore, one of them is still is 96. Then I know that, you know, it's very important us to understand that we have the limitation of what our ordinary, logical, linear aligned mind can really comprehend. Reality is much bigger. It's multi dimensional. And we go back to the space. Wendy. When we create the space with detox, we give room for new experiences. And that's why the aging process, in many ways, it's an amazing process. We mature, we become more refined. But if we are so focused on the fact that we have pain and we don't feel well, we kind of miss the value of it, you know, the refinement of it. And that's part of the process of letting go and creating room for the next level and letting go. So people who are meditating, it's very important. That maybe is the most important tip for meditation. Whatever you experience in meditation, don't hold to it. If it's a bad experience, you don't want to hold to it. If it's a great experience, you get really attached to it. There are a lot of meditation systems that are based on somebody having an amazing experience. Things are enlightened and teaching it, it is just an experience. It's don't, don't hold to it. Then it's a survival holding. So then everything becomes a flow. And when there is flow, there's less toxicity.

I have a question, Isaac, because a lot of what I have, more than one, but the one that I've sat with while you're talking is that most of the things you're referring to feel like they're emotional, mental, psychological, spiritual toxicities. How does the process of Letting go translate into the biochemical toxicities. What impact does it have? How do you see that on mercury and glyphosate and environmental toxins and pesticides? How does that relate?

It's a great question. It's interesting for my know, your process is called the five journeys. My journey is that on one level, without knowing, because my initial work on Galactic 3 was in cancer, I kind of stumbled around the fact that when you block it. No, I observed actually that when you block it, you affect inflammation and fibrosis. Early on, late 90s, I said, wow. So I kind of went into the biochemistry of changing the survival response. At the same time, I had this, this spiritual meditation journey, which I'm still on. And it comes together so it's all interrelated. We want to ask ourselves what causes us to look in? Yeah, it can be emotional, it can be psychological, and it can be pesticide and heavy metals. And what happens when we clean. And if we have a lot of biochemical toxicity, it will still affect us unless we are truly extraordinary people that are very rare. You know, they say like a star in the middle of the day, you know, it's not for us ordinary people that can handle toxicity. Nothing happens. Toxins will affect our membranes, like you said, will affect our biochemistry, will create a survival metabolism, anaerobic or aerobic glycolysis in the cell and will create diseases. So you got to address the biochemistry. But when you address it with an understanding that when you really relax, when you really open, then when your mind gets spacious, when you're not triggered by the same way, it's going to affect your neurotransmitter, your neuroendocrine system, your gut lining. Because the gut doesn't feel threatened, the biofilm becomes more relaxed, the healthy bacteria can be more dominant, There can be more diversity in the gut because there's less fighting. Well, the gut lining gets better. You get less autoimmunity, you absorb less toxins. Right. What does glyphosate do? It disrupts it. So that's why there are certain things we have to take. You know, I take my. My pectozol and my glypho detox every day. But I also try, no matter how busy I am, when I wake up in the morning before bedtime, I sit and I meditate. And one thing that I recognize when I meditate, so there's the experience of the regular openness of meditation, which I've trained for decades and decades. But then I go into the journey of seeing how it can affect my body. It's amazing. It's almost like I asked myself, why did it take 50 years for me to feel today what I didn't feel yesterday, but I know tomorrow it's going to be different. So. And I realized, wow, our ability to heal. You know, I had severe long haul Covid in August, severe because of certain unusual triggers. Almost died, I thought. And I get like paralysis in half of my body and I totally healed now. I used my tools, I used aphoresis, I used. But really what turned it around is the mind. And I find it. So there's a lot of people with COVID long haul and a lot of people have chronic diseases. People are holding to their diagnosis, they are identifying with their disease. So for me it was interesting because I was actually treating people who flew in with severe long haul because I treat it. And then they realize, oh my God, I like what they have, but worse. I mean, I basically canceled everything for weeks, except I would somehow come to see them because they came from far away. And then I realized, wow, you know, I have a choice. I can identify with it. I can freak out every time. It feels classically like an mi Chest pain. Pain I can understand. It's just the cytokines and this. So. And this addresses your question because I've been thinking about it before the interview today. And I'm also at a summit about regeneration, the treatings. So this really relates to what you are saying. So there is the change in the mind that will take time to be delivered to the biochemistry. It takes time. It's a mind body connection. It takes time. So the mind feels great, but the body is still sensitive over time. The mind is going to affect the biochemistry and there is a biochemistry that affect the mind. So with cleaning the biochemistry we have a choice. It is a little bit easier in some level. We take certain supplements, we do a certain diet. Might be tricky, but once we connect the mind to the heart, it starts moving faster.

How do we process what's the. What's the in to get the mind to the heart? People like, is there one technique or is there three techniques that.

Yeah. Yes. So really the. The key meditation technique is tongling. Then this meditation that takes in now the. The regular tongling, the universe that is taught for. No for 2000 years. Usually I don't share it in a podcast. Probably going to be the first time is that we take in suffering and we give love and compassion because that's what happened to the heart. So as part of my insight in meditation, it happened to me, a few years ago, I kind of discovered an inner tongling. A tongling that happened in the cellular level. It's not taught, you know, it's very different. It requires much more supervision and guidance, but it's very powerful. Because one thing for, you know, that we're all interested in, we talked about multi generational. We are made from countless being. If you look at each generation being 25 years, right? You go 50 years, it's four. You go 100 years, 16, you go 1600 years, 64. You know, it's like the chess game two, they didn't have enough grains. It's an infinite number. So infinite number made us these people. And the people that affected them epigenetically, Holocaust being an example, are actually affecting our genetics and epigenetics. They are affecting our cellular function. So their suffering is actually affecting us. We are holding it. We are suffering. You know, there's a famous saying in Hebrew which means our ancestors ate unripe fruits and the color of our teeth changed. Interesting how they. This is an epigenetic effect. So if we can find a way to do the tongling, but take their suffering that we are holding intracellularly, then it really speeds up. But it has to be done in the right way because a lot of stuff comes up. And I have had remarkable healing experiences in this, even with regular autonguine. One of my most amazing patients that I write on in my book in chapter six, the Heart of Survival, Charlie, who came with a metastatic prostate cancer and was with me for 18 years. He was a Vietnam vet, a commander in the helicopter that would fly very, very low. And then like they were like the bait. And then there were the planes up, and he would see the people who are trying to shoot him eye to eye. And he either gets shot down or he has to shoot him. He was the kindest man. He got shot down eight times in one year. He had to fly with his arm like tide, so he can fly. And so of course he had. You can imagine the ptsd. But when he learned his first time in a retreat. So he had pain from his prostate cancer in his pelvis for years. But when he learned it from the first time in retreat, the tonglen, it was just. Only in the clinic two days, just came during the day, one meal together and everybody went. But we had a strong relationship. I was with him also when he left his body. The story is all in the book, really worthwhile reading. And so when he came the next morning, he said, look, all night I went Back all the way to my childhood. Every trauma I had. I went back to Vietnam. And he woke up in the morning. He had no pain. But one thing I didn't write in the book, and I can mention here, he had the largest bowel movement he had in his life. When he woke up in the morning. Morning. He really let go in the gut what we hold, right? And at that point, he could visualize the people that he killed or tried to kill him, and he could see himself giving them love they didn't trigger. It's interesting, as I was driving to give him my last healing, was two days before he left his body. Then I was with him when he died and asked him, charlie, how you doing? Says, I'm doing great. I'm sending love to everybody, you know, including to your family. So he really transformed, you know, and lived for many years. So that's. That's. That's the power. So I hope to really. I call it open heart Medicine. Was supposed to be my first book in Hebrew, got delayed. So I came up with my second book, which has some elements, but that's really. I hope I stay healthy enough and. And focused enough to put out this and share it. Because, like one of my main spiritual teachers says, there is a certain stage in life when you went through training for decades and you really have something you can share. You know, that's why I took. I wrote my book only in my 60s, and I was asked to write a book in my 40s. But now it's time for me not to get lazy and to share, because it is making a difference in people's life and what you do and I do and we all do. We're trying to bring a different flavor to medicine and health. Right. I don't know if you're seeing it. I think it's a medical system as advanced as it is, it's really collapsing. Regular doctors don't have the space. We are back to space, Wendy. To think, to be creative, it's so automated. It's scary. It's really scary. I mean, if they just took a moment, and I'm not any better than them. They just happen to be in the wrong place for too many years. So we have a big job, all of us. And that's why, you know, that's really what. What drives me. What drives you. And we see the difference, right? You see the difference in the patient, and we don't get tired from doing medicine. It's amazing, you know, because of the difference. So really, thank you for what you're doing and should all, you know, support each other and keep moving forward?

Yeah. I mean, it really. When you were talking about your next book, it's like the appropriate transition in your career is now to contribute and bring it to more people so that your legacy continues.

Right. Yeah. That's why I do education. It's my third act. Yeah, definitely. That's the plan. Okay. Yeah, it was great. This is great.

Thank you. I mean, I think this is a good place.

We have another two hours to end.

Well, we're definitely having you back on the podcast. And we'll pick it up where we we left.

You won't have to twist my arm, I promise you.

We love playing with you, so it's fantastic. So I think we'll close it out here. Isaac, from the bottom of our hearts, thank you for being on the podcast today.

Thank you. Thank you.

And to the listeners, thank you for joining us for another episode of the Five Journeys podcast live. Like you matter today.

Thank you.

Thank you.

Sam.