Wendie Trubow, MD, MBA, IFMCPPresident at Five Journeys, Functional Medicine & Wellness Provider, Best Selling Author, Passionate Champion for Health

Why Women Lose Their Sex Drive Over Time @longevitymedicalclinic

3 Sept 2026 · 1 min

Watch on YouTube

1:06

In a short radio interview, Speaker A explains that women’s declining sexual interest in midlife is biologically driven. He outlines that women are born with roughly six million eggs, use about 500 over their reproductive years, and by age 45‑50 have essentially no viable eggs left, leading to a natural reduction in libido because the biological purpose of sex—reproduction—diminishes. He emphasizes that this loss of desire is normal and not something that needs to be “fixed.” Speaker B asks how listeners react, and Speaker A notes that male listeners react negatively to this explanation.

Chapters

One of the questions I always get from guys, never from the women, is my wife has lost interest in sex. How do I fix her? And my answer is, oh, you don't have to fix her. She's doing what women are designed to do. You know, from a biological standpoint, the purpose of sex is reproduction. Right. And women start with about 6 million eggs before they're, they're born in late gestation. They use about 500 of them during their reproductive life. But by the time they're 45 to 50, they essentially have no fertile eggs left. Those eggs have been in storage for 50 years and they don't last that long. And so when biology says you cannot reproduce anymore, the drive for sex normally fades. Okay. It's a, it's a reproduction thing. You know, from biology, as opposed to our society and our male wishes, the reality is that women are supposed to lose libido midlife. They just are.
Does that go over well with your radio listeners? Just out of curiosity.
The guys hate it. The guys hate it.