Wendie Trubow, MD, MBA, IFMCPPresident at Five Journeys, Functional Medicine & Wellness Provider, Best Selling Author, Passionate Champion for Health

How to Build Muscle During Menopause

27 Apr 2026 · 1 min

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A woman describes building muscle after menopause as pushing rocks uphill. A clinician explains that while most doctors prescribe topical testosterone cream to female patients, he uses weekly injectable testosterone cypionate instead, which he says dramatically accelerates muscle gains.

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I have to say, building muscles in menopause is like pushing rocks uphill. That's how I've felt about, about building muscle in menopause. And it's taken— I've been menopausal for, I think, almost 5 years, and it has taken me almost 3 to really dial in how to build muscle. It has been so challenging, you know, take a week off, lose muscle.
Yeah. Now, one thing that I'm doing, and I've been doing this now for about the past 4 or 5 years, is rather than giving women cream, testosterone cream, which I would say 90 90% of my patients are on it. But really, it's such an important critical hormone for women. So I have a lot of men that I take care of, and I've generally used testosterone cypionate with them, you know, an injection once a week. So I started doing that, Wendy, with women. And what I found, myself included, is that building muscle is so much easier. It just, it cuts the time in tenths.