Transcript excerpt from a YouTube video where Wendie Trubow, MD asks who should not take creatine. The respondent argues broadly that virtually no one should avoid creatine because the body requires it daily, endogenous synthesis is insufficient for all cells, and deficiency—especially in early life—can impair brain development and cognitive outcomes.
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Is there anyone who shouldn't take creatine? Because it sounds like kind of a broad brushstroke that most people could benefit from it. So who shouldn't take it?
I'm going to give what sounds like probably a biased answer, but I'm not aware of anybody who shouldn't take creatine because the body needs creatine every day. As I said, the body makes creatine, but it needs an exogenous source of creatine in order to have all of the cells supported nutritionally at a level that they're supposed to be. So there's no one who really can do without creatine. In fact, people who, especially early in life, are missing creatine, there can be retardation or mental prowess compromise in the youth, the children, if they don't get enough creatine. It's very important for brain development. I'm really not aware of anybody who can successfully live or optimally live without creatine.