Wendie Trubow, MD, MBA, IFMCPPresident at Five Journeys, Functional Medicine & Wellness Provider, Best Selling Author, Passionate Champion for Health

Signs You May Have a Hormonal Imbalance

23 Apr 2026 · 0 min

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In this segment of the YouTube video, the host interviews a clinician about recognizing hormonal imbalance. The clinician lists common early signs such as unexpected weight gain, low mood, prolonged premenstrual syndrome (lasting up to a week), increased fatigue, and shallower sleep. The discussion then shifts to the progression toward perimenopause, prompting the clinician to outline additional warning signs women should monitor as hormonal changes intensify. The overall purpose is to educate viewers on how to identify subtle hormonal disturbances early and to encourage proactive health management before full‑blown perimenopause symptoms develop.

In your practice, what are the main signs and symptoms that someone might have a hormonal imbalance?
So Lucy tells me, gee, I've gained 10 pounds, Prudence, and, you know, I'm feeling a little bit more down. I have, rather than a day or two of PMS, I'm having 7. I just feel more tired. So these are very typical symptoms. And I, and sleep is a little bit, you know, a little less deep.
As they process more into full-on perimenopause, What are the things women should look out for?
So those would be very similar, but more pronounced. So hot flashes are typical, quite depression, quite anxious, quite severe or moderate anxiety, 20 or 30 pounds of weight gain, sleeplessness. Prudence, I can't sleep. I'm awake at 3 o'clock. And also things like more obsessive behavior. That was actually one of my symptoms in perimenopause. Other behaviors such as a little paranoia, more fear, feeling less confident. Low sexuality. I love seeing patients in perimenopause, you know, right when the symptoms begin, because that's the time to correct hormones back to youthful levels.