Anne Truong MDMen's Sexual Health Doctor

How does Alprostadil work? #viral #shorts #menshealth #trimix #erectiledysfunctiontreatment #ed

25 Jun 2023 · 1 min

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A short YouTube video by Anne Truong MD explaining how Alprostadil (prostaglandin E1) treats erectile dysfunction: it relaxes smooth muscle in the corpus cavernosum by vasodilation of penile arteries. The speaker notes Alprostadil is rapidly metabolized (about 80% in ~5 minutes) with an estimated half-life of 5–10 minutes.

Questions this video answers

Approximately 80%.

About 5–10 minutes.

Prostaglandin E1 (a prostaglandin).

Chapters

The second medication is called Alprostatil. It's known as a group of medication called prostaglandin. E1 is a drug that a potent vasodilator or opens up blood vessels. And how it works in the corpus cavernosum or the penis muscle is that it relaxes the smooth muscle of the penis by opening up the arteries that lies within the penis. However, it is quickly metabolized, so it goes away quickly. 80% of it is being metabolized in about five minutes and half life is about five to ten minutes.