Anne Truong MDMen's Sexual Health Doctor

TRT Pellets vs. Injections: Which is Best? #TRT #MensHealth

12 Jul 2026 · 1 min

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In this segment, Dr. Anne Truong explains the testosterone pellet method for testosterone replacement therapy (TRT). She describes pellets as tiny, Tic‑Tac‑sized implants placed into the sub‑cutaneous fat of the buttock, typically 6–10 pellets per patient. The pellets are bioidentical testosterone derived from yam, releasing a steady daily dose, which she claims leads to better absorption, more consistent hormone levels, and fewer side‑effects compared with injectable testosterone cypionate. Dr. Truong briefly notes that TRT can also be delivered via injections or oral formulations, but emphasizes her preference for pellets due to their daily release profile and lower complication rate.

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The form that I particularly like is pellets, which is insertion of testosterone pellets, which is like the size of a Tic Tac. And I insert that on the buttock area in the fat area. Think of it like a reservoir where you embed the pellet in the fat of the buttock area and you put in several pellets. Some men will require between 6 to 10 pellets, and those pellets are releases testosterone every day and is bioidentical. Meaning that it is natural from yam and it releases testosterone every day and it has less complication than doing the injectable with testosterone cypionate. I prefer getting testosterone through pellet because it's better absorption, daily production, less side effects as well. So there's ways of injection testosterone, oral, and then pellet.