Dr. Conor Brady discusses Super Loren, an implant that blocks luteinizing hormone to reduce post-spay complications in dogs. After spaying, rising LH levels are linked to joint weakness, cruciate ligament ruptures, skin problems, and anxiety. Brady shares a case where a dog's chronic skin issues resolved with the implant, then returned when it wore off.
Is there any type of supplement, herbal or homeopathic, to help support a female dog who's been spayed? Discuss with your vet. There is a product available which is called Super Loren, which is used for canine castration. Okay, it blocks the release of LH, um, luteinizing hormone, luteinizing hormone from the pituitary. Basically, the feedback mechanism is that when you put that back in, so when you castrate or spay the female, so castrate the male, you remove the gonads. There is no feedback of the hormones back to the pituitary, and you get an increasing loop of LH being released trying to effectively force the gonads to produce more. They're not there, so it carries on producing. The majority of side effects seem to be associated with that LH rise. Like what side effects? So things like weakness in joints, so predisposition to having cruciate ruptures, to poor joint health, increased inflammation, increased skin itchiness, dryness, you've got issues with anxiety. All of these have LH receptors in the various centers which seem to be responsible for those drivers. So if you use supralaryngeal off-label for neutered cases, you can reduce some of those. So the first thing you usually see is the behavior returning to some degree of normality. So the excessive fears or anxieties reducing, but then you start to notice some of the others. I've got a great case where a dog who had skin problems actually had an implant. So you can have a lack of some of these androgens being produced by the gonads anyway naturally, and we saw that when he had the Supra laryngeal implant, all of his skin issues disappeared. And what they noticed was 2 years, 2 and a bit years in, as he reduced his supralaryngeal implant, his skin issues started to come back. They reimplanted and away they went. Supra laryngeal is off-label for this particular use. You'd have to discuss it with your vet.
