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In this segment Dr. Betty Murray explains that when using GLP‑1 agents such as triseptid, retratid, and semaglutide together with hormone replacement therapy (HRT) for women, individualized hormone testing is essential. She warns against blanket recommendations to add testosterone or estradiol without first measuring a patient’s baseline hormone levels. She emphasizes that both pre‑treatment and ongoing monitoring of androgen and estrogen levels are needed to ensure optimal dosing, which can help prevent cardiovascular disease, Alzheimer’s disease, and osteoporosis.

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