Peptides 101 : Deep dive into my favorite protocols

What the heck are peptides? I like to call them regenerative medicine because really what they're doing is they're going in to regenerate your cells back to their youthful state. Welcome to the Biohack Method. I am Lindsay Burwell. I break down the science, cut the fluff, and give you real tools to optimize your body with peptides, transdermal patches, and root cause biohacking that actually works. Welcome back to the Metabolic Method podcast. Today we're diving into all things peptides. Specifically, what are the protocols work with that I love, that I think are super regenerative. But before I dive into all my favorite peptides, I want to really build the foundation of what are peptides. And it's been so fun. I'll say like, in the, like, two years to see the evolution of like, people's understanding and just like knowledge of peptides. Two years ago, when I was first doing consults on peptides, I would say like one out of every five people I met with like, maybe knew about peptides, but really didn't know a lot. So there's a lot of like, education and whatnot going into explaining, like, what they are. Fast forward to now. I would say three out of every, maybe even four out of every five people that I meet, they've heard the word peptides. They kind of know. They still don't know all the things. It's really like a whole other world. I feel like sometimes it even feels like Chinese because the different protocols and the different names are just like so much. So if we really just break down what the heck are peptides? I like to call them regenerative medicine because really what they're doing is they're going into regenerate your cells back to their youthful state. So, so if you look at like the core of what a peptide is, they're just branch chain amino acids, which are really the building blocks of proteins that are naturally occurring already in our body. So these different peptide protocols that are that contain these very specific sequences of amino acids go in to target different areas of the body to bring them back to their youthful state. And truly, like, they are so profound. I, I call them the needle movers because it's like one of those things where like, I've tried everything, the supplements, my body's not absorbing it. I've tried the diet, the lifesty. We can implement these peptides because they go straight into the bloodstream and they are so effective. There's different ones to boost metabolism, to heal your gut, to help with anxiety and cortisol. There's some for sugar metabolism, there's some for fat burning. Truly like the sky is the limit. Immune boosting, you have it. Another thing that's really important to know about peptides is that they, there's a lot out there and there's different categories. So you have like your pharmaceutical peptides, right? These are the ones you go to your doctor, they write you a script, you go to a pharmacy and they write a that peptide for you. So you may know of Ozempic for example, so that is considered a pharmaceutical drug. However, there is one active peptide in Ozempic and that one is called semaglutide. So the rest of the Ozempic really is though the pharmaceutical components, fillers, preservatives, things like that. So the difference between that and like what a researching clinical peptide is that researching clinical peptides are just the amino acids. So what I've done is I've worked with a manufacturer to source these peptides and then we do third party testing for purity, for effectiveness. And that's where we have these great protocols to support you in the different things that you might be working on. I can't stress enough how quality does matter. I met with clients who have tried the more pharmaceutical route and had unwanted symptoms that were really intense. They couldn't control the dosing, they couldn't control the activation of the peptide. And so what's nice with our protocols is you can get them shipped direct to you. You get the bacterial static water to activate, you get to control the dosing and get to see the quality, right? These are just the amino acids with that third party testing. So super convenient, super accessible now and high quality. And I do, I like to tell clients I feel like in five years peptides are going to be more accessible. This is just me just projecting my own thoughts into the universe. But I feel like right now like you have like big pharma gatekeeping peptides which they really can't because you can't patent them because they're naturally occurring compounds. But you, and they make it seem like you need to go through this like pharmaceutical process to get them, but you really don't. You have research peptides, you have clinical peptides. And I really believe in five years like things are going to calm down sometimes where that you can probably even go to the grocery store to get them or like a health food store. I truly believe it. Like they are branched chain amino acids, they're just very potent, but there's nothing like crazy about them. You Just can't patent them.

So they get a little.

There's a little gray area with them. Okay, so here are the different protocols on the peptides that I work with that I'm completely obsessed with. So we have the GLPs. I'm going to explain, like, how that works because I'm very passionate about jlp. We have NAD and energy protocol. We have a gut healing protocol. We have an anti aging protocol. Cortisol fix. Hello. It's so amazing. The focus protocol. Like, so much better than ADHD medicine. The GLOW protocol. This is all the rage and like the aesthetic world, the facial world, Hormone balancing protocol. So much better than taking bioidentical hormones. Immunity protocol. The liver detox, the longevity, the metabolism, which we've actually rebranded as the shredder because it literally shreds you. The repair and then the tanning. Like, I have clients are like, I don't know, I want them all. Like, me too. They're so fun. And it is like cycling, dosing, all that is so important. But there is, like, a lot of great things you can do with these. So let's dive into these. So we have GLP 1, 2 and 3. I want to explain the history of GLP. So the GLPs have been around a long time. Semaglutide, right? OIC, this peptide, this, like, drug was actually created for diabetics, right, to help regulate blood sugar and insulin. And what happened a few years ago was that biohackers and people who understood, like, biology and fat burning knew that, wait, if you want to burn fat, it has so much to do with blood sugar and insulin. Why aren't we utilizing these diabetic peptides to tap into our own biology, to.

Flip on that switch for more metabolic flexibility?

Why aren't we, like, microdosing that? Why aren't we utilizing that more on a preventative basis before we get to the point of diabetes, where we get to the point of like, Alzheimer's, things like that? Like, why can we use like a tool instead of something to, like, cure after it's already become a problem? And so that's where a few years ago, so huge people were taking it.

They were losing tons of weight. Now we've learned a lot since then.

We've learned, okay, you don't want to macro dose this. You don't want to take the standard dose. Maybe the pharmaceutical route may or may not be for you diet. Exercise is key here. Like, it's the most, like, low effective.

Dose is where the money's at. But here's what's amazing. I want to go back to.

GLPs were not created for weight loss. They were created to heal blood sugar and insulin. But the byproduct of a healthy cell.

When you have blood sugar and insulin.

Fixed, is weight loss. Like the you lose weight when your.

Body is healthy, you don't like, lose.

Weight, and then you get healthy. We have that turned around sometimes. And so that is so power powerful to know. And that's why so many people experience.

Such amazing results on GLPs, because literally.

They'Re fixing the root of the problem.

Which is blood sugar and insulin.

And I'll tell you a little secret.

And most metabolic diseases is rooted in this. You can almost fix everything in your body if you fix insulin and glucose. And they say 97 of Americans are metabolically inflexible, meaning they have a sugar metabolism problem. So all of us truly can benefit.

From this because of the way of the world we live in.

Our diet, our sleep, our stress, our.

Lack of micronutrients in our soil.

The list truly goes on. We're snacking, we're not. We're eating late, we're not fasting. We're not living in, like, circadian rhythm and how our body was biologically designed.

To heal and thrive, so it affects blood sugar. So let's talk about the differences.

I get this all the time. And I will do a more of.

A deep dive, like on the differences.

But just to give you a taste.

So you have GLP1, semaglutide, GLP2, that.

Is tirzepatide, and GLP3, which is retatrutide.

Okay, quick pause, because I need to tell you about something that's literally changing the game for metabolism, energy detox, and even your immune health. You guys know I do not waste my time with gimmicks. And that is why I created the patch method. Also because people are tired of taking pills. All the clients I have seen, we tired of taking the pills, and we don't even know if we're actually absorbing it.

These are all amazing. How you break this up is GLP1.

Somali is going to target hunger.

It's going to blunt the hunger. It's going to take away the sweets.

The treats, the cravings for carbs and all the sugars.

Right? Which is so nice. So many people say it's like the food noise finally went away, and I can think clearly. It's like the food noise went away and I'm not prisoned by what to eat, what not to eat. There is A very freeing experience when you are not obsessively thinking about food. Not that everyone is, but I find some of us are, right. And so having that support is amazing. The byproduct of you not eating all the time and snacking, all the sugars is going to be regulated. Blood sugar, insulin is going to be. Reduction of inflammation is going to be weight loss. So semaglutide, tried and true. So amazing. And a lot of people have great results with that. Let's talk about tirzepatite. So the difference between tirzepatite and semaglutide is that again, Semaglutide is just GLP1, just appetite. Tirzepatide is a GLP and the GIP, which is more insulin and blood sugar. So you're getting here, hitting two receptors, and it's doing a little bit more of a medicinal thing. What I will say is the appetite curve is not as blunt. So for somebody who really needs that food noise dialed in, maybe even just for a few months, maybe during the holidays, they will do better on semaglutide in that sense. But GLP2 is more mild, symptomatically, meaning if you have gastrointestinal problems, if you're sensitive like that, semaglutide can do some adjusting in that area and you might feel a little more even on a microdose. So tris appetite could be really powerful, but really, it enhances metabolism, improves glucose regulation, optimizes lipid profiles, it can improve sleep. There's so many benefits. I can go on and on. I've seen clients get off thyroid medication, autoimmune stuff, heal itself, migraines go away. Obviously, the weight loss is amazing. Mental clarity, food freedom. There's so many amazing studies. Even I could just go on and on about, like, new neural pathways in the brain being created from this peptide. It's just. It's the chef's kiss. It really is. Okay, GLP3, so this one's red, a true tide. And this one's really powerful because this one is the new girl on the block.

And actually, you guys, I think we're.

Going to be seeing more like, more exciting GLPs in the future. This is just the beginning. And it makes me excited because I'm all about blood sugar. But GLP3, how I would categorize it is basically you have hitting three receptors, right? So it's hitting the glp. So that's the appetite curve and the suppression of those cravings for the sweets.

And treats and carbs.

It's also hitting that gip, which is the insulin and glucose. So super medicinal for sugar metabolism. Right. And then it's also activating a glucagon receptor, which is what is happens with liposis where your body converts fat into energy. So what I see with clients is by week three they're like, I have so much energy because literally their body is in a fat burning machine.

I have seen clients just, just push.

Through a plateau and they activate that receptor because their body is really utilizing that fat energy source. What I will say is because it's hitting three receptors, the appetite curve is not as blunt. And that can be confusing for clients because they're like, I'm still hungry. So it feels like it's not working when actually it's a triple threat. It's just activating three different things.

So think about it.

Five units of GLP1 would be like, for a five unit of GLP2 would be like two and a half each, right? So it's like splitting between two things and then for GLP3 it's splitting into three. So it's like you sometimes need more. If you want more napko, you can also co dose it with both GLP1 GLP3. There's so many ways to like dose.

And dice and Honestly I think GLP3 is amazing. But it truly like which one's best for you. It comes down to like you, your current symptoms, what you're sensitive to, your craving profile. Like some people just don't get cravings. Perfect. You should do GLP3.

It's amazing.

Any kind of plateaus you've been on and also cycling in between the different ones is also really powerful. Okay, let's talk about NAD and the energy protocol. So anytime I see clients, when I do metabolic scans for them, if they have an energy production issue, they need some nad. And this is the perfect way to do it because it gets right into the bloodstream. You cannot take NAD orally. You will not absorb it. And so this one is just boosting cellular energy by enhancing mitochondrial function. It increases vitality, improving overall physical performance. We all of our cells need energy to function. And so NAD is so powerful for that. It also is really great for aging. I it's really great for anti aging, especially when you hit 40s, 50s and NAD slowly starts to decline. We need energy. Our cells need energy to do all their jobs. Let's look at the next one. We are looking at the oral gut healing protocol. This one's amazing. BPC right through your gut. So if you have any leaky gut, inflammation in the gut, and you want to target that gut repair, you can do an oral one. And that one is phenomenal. The anti aging protocol. So this one will help to stimulate natural growth hormone in the body. This does support cellular repair and regeneration. It improves skin elasticity, muscle tone, body composition. But here's why it's doing that. So when you are like a baby, you're born, you have all this growth hormone, right? That's you have lots of energy, you sleep hard, all that good stuff, you build muscle. And when you get older, growth hormone really starts to drop. At 45, 50 years old, that's where you could start feeling. I'm just like tired. I can't lift it.

Heavy.

I'm not recovering well. I don't sleep good. That's where, like when I see people get on the CJC IPamorlin, boom. They feel like they're back in their 30s. They feel like they're back in their 20s. They're lifting heavier. When you're lifting heavier, when you're doing more, when you're more active. The byproduct is better metabolism, better body composition, better sleep, better recovery. So all these benefits are truly just coming from the increased growth hormone. But what I will say, I don't really think women or men really need to get on this one until you've hit like mid-40s, because that's really where growth hormone starts to go down. And I'm like, save your money for something different. Until you hit that time frame and you just like tap into your knowing and your body to know, okay, I actually do need the growth hormone. When you do need it, you know it and it feels amazing. Little testimony here. My grandma loved to be loved to just lay in bed all day, no joke. Like, we were like, do something, exercise, get out of bed all the time. She wasn't sleeping sick. She has had no energy. She's 75. I don't know. Anyway, we just got her started on this. She's another woman. She goes out for coffee, goes out for walks, she swims. She told me, literally, she feels like she was just given a new life, a second chance to live. And I'm like, oh my gosh, grandma. Like, this is amazing. Truly. It was like the coolest statement she has ever said. The cortisol fix. Okay, so this one's amazing. If you have stress, if you're running on adrenals, if you are like looking into antidepressant and anxiety, start with this, okay? Antidepressants, anti anxiety, There is a time and a place, and I love that we have access to that. But what's great and what's different is let's do some internal healing and peptides and go in to do that regenerative work versus taking something to curb all that. So it reduces stress, it regulates cortisol levels, which helps with hormonal balance.

Right.

It improves cognitive function, focus, mental clarity. It boosts stability, overall brain health. Like, Truly SMAX is the way to go if you're needing some cortisol, tlc, the focus one. Okay, if you need adhd, if you cannot focus, or if you have adhd, you cannot focus, or you're working through a project or maybe, you know, you've been on some medication for adhd. Try the Focus Protocol. This is celink. This one also reduces anxiety and stress, but it really enhances, like, focus, memory and cognitive performance. I'm totally going to take this, like, before I do my podcast live launch. I just think it's going to be so great because it's going to dial in that focus. And who doesn't love it? That. So that's the Focus Protocol. The GLOW Protocol. We love this one. This one is. It's actually purple. It's so amazing. It's a copper peptide, which, if you really dig into PubMD in the literature on this, it actually increases stem cell activity in the body. There's a lot of, like, autoimmune stuff that it's going in to work on, but it's known in the beauty and cosmetic industry as Truly the glow. So it stimulates collagen, elastin, it helps with hair regrowth. I call it like the better Botox. Better than Botox. I've actually never spent money go to the floor because I put my money into this Glow Peptide. It strengthens hair follicles, it supports skin repair. I've actually even had some clients do it in their gut and seen really great results. So we love the GLOW Protocol. The next one is the hormone balancing on this one. I am so tender to. Because I am just not. I don't do hormone replacement therapy, and I feel like it's being pushed. Younger and younger women are like, I have no T and you're 30 years old and all the things. And so the difference between taking Kiss Pep and the hormone peptide versus, let's say hormone replacement therapy or biopsy bioidentical hormones is that bioidentical hormones are replacing your body's hormones with exogenous hormones, right? Saying, here you go, body, here it is. In the direct form, you don't need to do it anymore, you don't make it anymore. We got you. Versus a hormone peptide goes in to repair that HPA axis responsible for estrogen, progesterone, testosterone. So your body will be able to naturally recreate those hormones on its own. So it's amazing for reproductive health, libido overall, just endocrine function. I always tell people, like do one or two cycles of this and then maybe consider the hrt. I really think it's such a great way to go. Especially because you could overdose very easily, get dysregulated on estrogen. Like the whole HRT world needs to be more monitored, I believe. Okay, the immunity protocol. I'm going to have this on deck for cold and flu season. This one is going to strengthen your body's immune response and enhance the body's ability to fight off infections. Who doesn't want that? Oh my gosh, this winter this is going to be amazing. It also reduces inflammation, supports recovery from illness. It's just like overall a huge boost of immune support. And that is thymus and alpha one. It is going to be such a great go to for me this winter. The liver detox. I take this one on the regular. I love me some glutathione. And you cannot take it orally. It has to be either liposomal injection or via transdermal delivery. It promotes liver detoxification, protects against oxidative stress on our cells, supports healthy skin, immune function, cellular repair, and she's an overall great antioxidant and support for detox detox that is glutathione. Let's look at the longevity protocol. If you're into longevity, that's your thing. I can't tell you enough about epitalin. So that one just supports healthy aging by literally. It's been shown to extend telomere length, extend your lifespan. How crazy is that? Just through cellular regeneration. It also can improve sleep, improves overall, just like rest in like rest quality, all that good stuff. This is like the tried and true longevity one. The next one is the metabolism boost which we are now calling the shredder because it literally shreds bloods, all the fat. It's doing three different things though. So it has, it has some B vitamins methylated, we love that. For mood, metabolism, energy. It also has L carnitine and arginine, which is great for fat metabolism to support weight loss, body composition, literally turning that fat into energy. It also supports liver function because it has cloning and methylone. It's going to be those co factors for your liver detox. So think energy detox and fat burn. Literally. It's so good.

I will take it for a workout.

And you'll have to drag me out of the gym because how good I feel. And it is a red vial so it looks fun. And then we have the repair protocol. So this one basically just accelerates healing of the muscles and tissues. We combine it with BPC157TB500 for a synergistic powerhouse. It's going to reduce inflammation, promote faster recovery from injury, support joint health, flexibility, overall tissue repair. It is truly so good. All the athletes use it when they get go down with any kind of ailment because no one has time to be down. Right. So if you, you feel like you are not recovering well, maybe you have a past injury that's not recovering well. This is such a great protocol for you. Or maybe you want to use it for inflammation. I've seen people do it for that. For workout inflammation, post recovery. It like the sky's the limit. It's just awesome. Okay, tanning one. This is the last one. People think this is a joke, but it's for real and I use it. I have not touched myself tanner since January and it is July. August. It's August. Okay.

So what it does is it increases.

A melanin in your skin. So people who have that like naturally glowy tan skin have more milanin than someone who's like me who has more fair skin. So what the peptide doing, it's increasing melanin so you naturally become tanned. And it's so amazing. It is like a deeper, long lasting tan. It also provides UV protection. This is so crazy because I wore this in Hawaii or I used it before I went to Hawaii. I did not get burned and I was like trying to get burned.

I was like burned like this for an experiment.

Like it's not good to get burned.

But it was truly amazing.

And all summer I had the best, I still have the best tan. So you start with daily dose and you reach your desired tan and then once you do, you can titrate back.

Down to more maintenance.

So maybe instead of every day do once a week or even once a month.

I don't even take it once a month.

I take it like when I whenever truly I'm like, oh, I need a little tanning boost today. I'll take it and boom, I'm great. So support skin health reduces sun damage. Truly love, love, love that one. Of course.

Medical disclaimer.

All of this information is just from.

My own research, from my own education and just from my own anecdotal data from working with clients using it on myself.

And if you have any questions for.

Sure ask someone that you trust, a.

Provider, whoever, do your own due diligence.

Tap into your own inner knowing, your own body. Your body will tell you what you need and what feels right. But I just love to share the information about peptides. I truly believe they are a game changer. I have seen them totally transform my clients lives. And if you do decide to work with us with peptides, I work with.

The natural peptides, these are just the.

Amino acid peptides and I have created.

A peptide portal but which just gives.

More like community support resources to maximize your results from nutrition to exercise to supplements to activate and enhance your results along with community chat, weekly coach or weekly trainings. Truly all that unique. So I do believe like peptides are.

Not supplements can go to the store.

And buy and do whatever like having guidance, having support really makes a difference and can make or break your results. And if you ever have any questions.

Please feel free to reach out.

You can DM me, you can go to support thenatural peptides.com but I hope you found this helpful and I'm sure we will be in touch so soon.

That's it for today's episode of the Biohack Method. If this lit something up in you, do me a favor, share it. Tag me at Lindsay Burwell Wellness and drop a review. Ready to dive deeper? Head to the show notes for Peptides patches and programs that are changing the game for high performing women like you.