Dr. Nyree Penn, DHSc, CAAInventor | Founder | CEO, 🌙 NSOMNIA Sleep · ✨ NeuroRestorative Sleep Scientist | Anesthesiologist Assistant (CAA) | Founder & CEO 🌙 NSOMNIA Sleep Centers™ | Author | Speaker 🌟Redefining Sleep for NeuroRestorative Brain Health

New Episode Dropped 🚨🚨🚨 #shorts

11 Apr 2026 · 0 min

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0:29

In this brief health snippet, Nyree Penn explains how decreasing estrogen levels during aging suppress serotonin production. She highlights that about 80% of the body’s serotonin is synthesized in the gut, and the combined drop in estrogen and gut‑derived serotonin contributes to menopausal women waking up during the night. The segment links hormonal change to sleep disruption, offering a concise physiological explanation for a common menopausal symptom.

Estrogen is another big one. It also affects serotonin, right? So as we get older, if our estrogen goes down, it suppresses our serotonin as well. The thing with that is serotonin is actually made in our gut. 80% of our serotonin is made in our gut. So if our serotonin levels are low and then our estrogen levels are low, we have an ongoing problem where women in those menopausal stages tend to wake up in the middle of the night.

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