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In this YouTube short, Nyree Penn, MHSc., CAA, explains the hyperarousal endotype, a sleep‑related phenotype characterized by a constant state of being "wired and tired." Individuals with this endotype are chronically anxious, hypervigilant, and perpetually on high alert. Penn describes their neurochemical profile—elevated acetylcholine, cortisol, and adenosine—highlighting how this heightened arousal interferes with normal sleep, leading to fragmented or poor‑quality rest. The segment serves to raise awareness of this specific endotype and its implications for sleep health.

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