Dallas Bragg argues that crystal meth targets individual brain chemistry and insecurities in a way other drugs don't, first triggering euphoria then amplifying paranoia and psychosis. He says this mechanism makes recovery uniquely difficult.
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Listen, crystal meth has an energetic intelligence. I'm probably going to get a lot of comments, and I'm probably going to get a lot of blocks for saying this. It's scientifically proven that it's harder to recover from crystal meth than any other drug, and here's why: This substance is intelligent. It knows how to go into your brain, into your specific brain chemistry and neurons, and pull out your insecurities, what matters to you specifically. Whatever your insecurities are, whatever your specific beliefs are, it goes in there, takes it out, and expands it. If there's a predisposition for mental illness like schizophrenia, it pulls that out and runs with it. But the trick is, in the beginning, it makes you feel so good and so indestructible and a relief from your insecurities. After you're pulled in, you end up paranoid, in psychosis, and hating yourself.